Potential role of hematopoietic stem cell transplantation in children with secondary acute lymphocytic leukemia

A. S. Melemed, G. Vance, P. K. Kotylo, F. O. Smith

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Secondary acute lymphocytic leukemias (ALL) are uncommon events in the pediatric patient population. There are few detailed reports on the laboratory characteristics and clinical course of patients with secondary lymphocytic leukemia. Historically, these patients have had a poor outcome. We report two patients treated at one institution who developed treatment-related secondary ALL. Both patients underwent hematopoietic stem cell transplantation, one with a compatible unrelated donor cord blood unit and one with an HLA-matched sibling donor bone marrow. One of the two patients survives disease-free 3 years after transplantation.

Original languageEnglish (US)
Pages (from-to)173-175
Number of pages3
JournalBone marrow transplantation
Volume29
Issue number2
DOIs
StatePublished - Jan 1 2002

Keywords

  • Bone marrow transplantation hematopoietic stem cell transplant
  • Children
  • Leukemia
  • Secondary acute lymphocytic leukemia
  • Treatment-related acute lymphocytic leukemia

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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