Practical Considerations of Renal Biopsies in Critical Care Patients

Jwalant R. Modi, Helen Liapis, Bruce A. Molitoris, Michael T. Eadon

Research output: Chapter in Book/Report/Conference proceedingChapter


Acute kidney injury presents a wide differential of potential causes, including glomerular, tubular, and interstitial processes. Often a careful history, physical exam, and laboratory evaluation are sufficient to make a diagnosis. However, a kidney biopsy is sometimes necessary to make or confirm the diagnosis or stage the level of disease. Because therapies vary from conservative medical care to aggressive immunosuppression, a definitive diagnosis from a kidney biopsy can direct and improve care. The purpose of this chapter is to review the indications, contraindications, various modalities, and complications associated with a renal biopsy. Special emphasis is placed on strategies to lower the risk of adverse events in critically ill patients. The diagnosis and management of various diseases commonly diagnosed by kidney biopsy are also discussed.

Original languageEnglish (US)
Title of host publicationCritical Care Nephrology
Subtitle of host publicationThird Edition
PublisherElsevier Inc.
ISBN (Electronic)9780323449427
ISBN (Print)9780323449427
StatePublished - Jan 1 2019


  • Acute tubular necrosis
  • Hematuria
  • Intensive care unit
  • Perinephric hematoma
  • Transjugular renal biopsy

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Practical Considerations of Renal Biopsies in Critical Care Patients'. Together they form a unique fingerprint.

  • Cite this

    Modi, J. R., Liapis, H., Molitoris, B. A., & Eadon, M. T. (2019). Practical Considerations of Renal Biopsies in Critical Care Patients. In Critical Care Nephrology: Third Edition (pp. 167-173.e1). Elsevier Inc..