Predictors and moderators of parent training efficacy in a sample of children with autism spectrum disorders and serious behavioral problems

Cristan Farmer, Luc Lecavalier, Sunkyung Yu, L. Eugene Arnold, Christopher J. McDougle, Lawrence Scahill, Benjamin Handen, Cynthia R. Johnson, Kimberly A. Stigler, Karen Bearss, Naomi Swiezy, Michael G. Aman

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The Research Units on Pediatric Psychopharmacology - Autism Network reported additional benefit when adding parent training (PT) to antipsychotic medication in children with autism spectrum disorders and serious behavior problems. The intent-to-treat analyses were rerun with putative predictors and moderators. The Home Situations Questionnaire (HSQ) and the Hyperactivity/ Noncompliance subscale of the Aberrant Behavior Checklist were used as outcome measures. Candidate predictors and moderators included 21 demographics and baseline measures of behavior. Higher baseline HSQ scores predicted greater improvement on the HSQ regardless of treatment assignment, but no other predictors of outcome were observed. None of the variables measured in this study moderated response to PT. Antipsychotic medication plus PT appears to be equally effective for children with a wide range of demographic and behavioral characteristics.

Original languageEnglish
Pages (from-to)1037-1044
Number of pages8
JournalJournal of Autism and Developmental Disorders
Volume42
Issue number6
DOIs
StatePublished - Jun 2012

Fingerprint

Antipsychotic Agents
Demography
Psychopharmacology
Autistic Disorder
Checklist
Outcome Assessment (Health Care)
Pediatrics
Research
Autism Spectrum Disorder
Surveys and Questionnaires
Problem Behavior
Therapeutics

Keywords

  • Autism
  • Moderator
  • Parent training
  • Pervasive developmental disorder
  • Predictor
  • Risperidone

ASJC Scopus subject areas

  • Developmental and Educational Psychology

Cite this

Predictors and moderators of parent training efficacy in a sample of children with autism spectrum disorders and serious behavioral problems. / Farmer, Cristan; Lecavalier, Luc; Yu, Sunkyung; Arnold, L. Eugene; McDougle, Christopher J.; Scahill, Lawrence; Handen, Benjamin; Johnson, Cynthia R.; Stigler, Kimberly A.; Bearss, Karen; Swiezy, Naomi; Aman, Michael G.

In: Journal of Autism and Developmental Disorders, Vol. 42, No. 6, 06.2012, p. 1037-1044.

Research output: Contribution to journalArticle

Farmer, C, Lecavalier, L, Yu, S, Arnold, LE, McDougle, CJ, Scahill, L, Handen, B, Johnson, CR, Stigler, KA, Bearss, K, Swiezy, N & Aman, MG 2012, 'Predictors and moderators of parent training efficacy in a sample of children with autism spectrum disorders and serious behavioral problems', Journal of Autism and Developmental Disorders, vol. 42, no. 6, pp. 1037-1044. https://doi.org/10.1007/s10803-011-1338-2
Farmer, Cristan ; Lecavalier, Luc ; Yu, Sunkyung ; Arnold, L. Eugene ; McDougle, Christopher J. ; Scahill, Lawrence ; Handen, Benjamin ; Johnson, Cynthia R. ; Stigler, Kimberly A. ; Bearss, Karen ; Swiezy, Naomi ; Aman, Michael G. / Predictors and moderators of parent training efficacy in a sample of children with autism spectrum disorders and serious behavioral problems. In: Journal of Autism and Developmental Disorders. 2012 ; Vol. 42, No. 6. pp. 1037-1044.
@article{14a8e419002948eabdac48604f534603,
title = "Predictors and moderators of parent training efficacy in a sample of children with autism spectrum disorders and serious behavioral problems",
abstract = "The Research Units on Pediatric Psychopharmacology - Autism Network reported additional benefit when adding parent training (PT) to antipsychotic medication in children with autism spectrum disorders and serious behavior problems. The intent-to-treat analyses were rerun with putative predictors and moderators. The Home Situations Questionnaire (HSQ) and the Hyperactivity/ Noncompliance subscale of the Aberrant Behavior Checklist were used as outcome measures. Candidate predictors and moderators included 21 demographics and baseline measures of behavior. Higher baseline HSQ scores predicted greater improvement on the HSQ regardless of treatment assignment, but no other predictors of outcome were observed. None of the variables measured in this study moderated response to PT. Antipsychotic medication plus PT appears to be equally effective for children with a wide range of demographic and behavioral characteristics.",
keywords = "Autism, Moderator, Parent training, Pervasive developmental disorder, Predictor, Risperidone",
author = "Cristan Farmer and Luc Lecavalier and Sunkyung Yu and Arnold, {L. Eugene} and McDougle, {Christopher J.} and Lawrence Scahill and Benjamin Handen and Johnson, {Cynthia R.} and Stigler, {Kimberly A.} and Karen Bearss and Naomi Swiezy and Aman, {Michael G.}",
year = "2012",
month = "6",
doi = "10.1007/s10803-011-1338-2",
language = "English",
volume = "42",
pages = "1037--1044",
journal = "Journal of Autism and Developmental Disorders",
issn = "0162-3257",
publisher = "Springer New York",
number = "6",

}

TY - JOUR

T1 - Predictors and moderators of parent training efficacy in a sample of children with autism spectrum disorders and serious behavioral problems

AU - Farmer, Cristan

AU - Lecavalier, Luc

AU - Yu, Sunkyung

AU - Arnold, L. Eugene

AU - McDougle, Christopher J.

AU - Scahill, Lawrence

AU - Handen, Benjamin

AU - Johnson, Cynthia R.

AU - Stigler, Kimberly A.

AU - Bearss, Karen

AU - Swiezy, Naomi

AU - Aman, Michael G.

PY - 2012/6

Y1 - 2012/6

N2 - The Research Units on Pediatric Psychopharmacology - Autism Network reported additional benefit when adding parent training (PT) to antipsychotic medication in children with autism spectrum disorders and serious behavior problems. The intent-to-treat analyses were rerun with putative predictors and moderators. The Home Situations Questionnaire (HSQ) and the Hyperactivity/ Noncompliance subscale of the Aberrant Behavior Checklist were used as outcome measures. Candidate predictors and moderators included 21 demographics and baseline measures of behavior. Higher baseline HSQ scores predicted greater improvement on the HSQ regardless of treatment assignment, but no other predictors of outcome were observed. None of the variables measured in this study moderated response to PT. Antipsychotic medication plus PT appears to be equally effective for children with a wide range of demographic and behavioral characteristics.

AB - The Research Units on Pediatric Psychopharmacology - Autism Network reported additional benefit when adding parent training (PT) to antipsychotic medication in children with autism spectrum disorders and serious behavior problems. The intent-to-treat analyses were rerun with putative predictors and moderators. The Home Situations Questionnaire (HSQ) and the Hyperactivity/ Noncompliance subscale of the Aberrant Behavior Checklist were used as outcome measures. Candidate predictors and moderators included 21 demographics and baseline measures of behavior. Higher baseline HSQ scores predicted greater improvement on the HSQ regardless of treatment assignment, but no other predictors of outcome were observed. None of the variables measured in this study moderated response to PT. Antipsychotic medication plus PT appears to be equally effective for children with a wide range of demographic and behavioral characteristics.

KW - Autism

KW - Moderator

KW - Parent training

KW - Pervasive developmental disorder

KW - Predictor

KW - Risperidone

UR - http://www.scopus.com/inward/record.url?scp=84863873079&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84863873079&partnerID=8YFLogxK

U2 - 10.1007/s10803-011-1338-2

DO - 10.1007/s10803-011-1338-2

M3 - Article

VL - 42

SP - 1037

EP - 1044

JO - Journal of Autism and Developmental Disorders

JF - Journal of Autism and Developmental Disorders

SN - 0162-3257

IS - 6

ER -