Predictors of calcium retention in adolescent boys

Kathleen M. Hill, Michelle Braun, Mark Kern, Berdine R. Martin, James W. Navalta, Darlene A. Sedlock, Linda McCabe, George P. McCabe, Munro Peacock, Connie M. Weaver

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Context: The relationship between calcium (Ca) intake and Ca retention in adolescent boys was recently reported. Objective: This study evaluated the influence of Ca intake, serum hormone levels, biomarkers of bone metabolism, habitual physical activity, habitual Ca intake, and physical fitness on Care tention in the same sample. Design: This study was a randomized, cross-over design that consisted of two 3-wk metabolic balance periods. Setting: The study took place on a university campus as a summer camp. Patients or Other Participants: A total of 31 American white boys (13-15 yr) participated in the study. Interventions: Each subject consumed a controlled diet with one of five high-low Ca intake pairs that ranged from 670-2003 mg/d, which was manipulated utilizing a fortified beverage. Main Outcome Measures: Ca retention was determined by Ca intake minus urinary and fecal Ca excretion during each balance period. Results: Ca intake explained 21.7% of the variability in Ca retention, and serum IGF-I concentration explained an additional 11.5%. Other serum hormone levels did not significantly add to the model. Biomarkers of bone metabolism, habitual physical activity, habitual Ca intake, and physical fitness were not significant predictors of Ca retention in adolescent boys. Conclusions: IGF-I, a regulator of growth during puberty, is an important predictor of Ca retention in adolescent boys. However, dietary Ca intake is an even greater predictor of Ca retention during this period of growth.

Original languageEnglish
Pages (from-to)4743-4748
Number of pages6
JournalJournal of Clinical Endocrinology and Metabolism
Volume93
Issue number12
DOIs
StatePublished - Dec 2008

Fingerprint

Calcium
Physical Fitness
Biomarkers
Insulin-Like Growth Factor I
Metabolism
Bone
Serum
Hormones
Exercise
Bone and Bones
Dietary Calcium
Beverages
Puberty
Nutrition
Growth
Cross-Over Studies
Outcome Assessment (Health Care)
Diet

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Endocrinology
  • Biochemistry, medical
  • Endocrinology, Diabetes and Metabolism

Cite this

Hill, K. M., Braun, M., Kern, M., Martin, B. R., Navalta, J. W., Sedlock, D. A., ... Weaver, C. M. (2008). Predictors of calcium retention in adolescent boys. Journal of Clinical Endocrinology and Metabolism, 93(12), 4743-4748. https://doi.org/10.1210/jc.2008-0957

Predictors of calcium retention in adolescent boys. / Hill, Kathleen M.; Braun, Michelle; Kern, Mark; Martin, Berdine R.; Navalta, James W.; Sedlock, Darlene A.; McCabe, Linda; McCabe, George P.; Peacock, Munro; Weaver, Connie M.

In: Journal of Clinical Endocrinology and Metabolism, Vol. 93, No. 12, 12.2008, p. 4743-4748.

Research output: Contribution to journalArticle

Hill, KM, Braun, M, Kern, M, Martin, BR, Navalta, JW, Sedlock, DA, McCabe, L, McCabe, GP, Peacock, M & Weaver, CM 2008, 'Predictors of calcium retention in adolescent boys', Journal of Clinical Endocrinology and Metabolism, vol. 93, no. 12, pp. 4743-4748. https://doi.org/10.1210/jc.2008-0957
Hill KM, Braun M, Kern M, Martin BR, Navalta JW, Sedlock DA et al. Predictors of calcium retention in adolescent boys. Journal of Clinical Endocrinology and Metabolism. 2008 Dec;93(12):4743-4748. https://doi.org/10.1210/jc.2008-0957
Hill, Kathleen M. ; Braun, Michelle ; Kern, Mark ; Martin, Berdine R. ; Navalta, James W. ; Sedlock, Darlene A. ; McCabe, Linda ; McCabe, George P. ; Peacock, Munro ; Weaver, Connie M. / Predictors of calcium retention in adolescent boys. In: Journal of Clinical Endocrinology and Metabolism. 2008 ; Vol. 93, No. 12. pp. 4743-4748.
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