Abstract
Objective: To determine variables predictive of glycemic control in a large population of pediatric patients with type 1 diabetes on continuous subcutaneous insulin infusion (CSII). Methods: Charts of patients on CSII for ≥1 year were reviewed. "Good" control was a priori defined as HbA1c ≤9% in patients under 12 years of age, and ≤8% in patients over 12 years. Results: Ninety-three patients were identified (57 girls and 36 boys). Their mean age at pump start was 11.6 ± 3.1 years with duration of diabetes of 4.7 ± 3.1 years. Average time on pump therapy was 2.4 ± 0.8 years. HbA1C decreased from 8.7 ± 0.9% prior to pump therapy to 8.3 ± 0.6% while on CSII (p < 0.01). Despite analysis of a large number of possible predictors, only number of basal rates (4.4 versus 3.4) and younger age (10.0 years versus 13.1 years) correlated with good control. Conclusion: Only younger age and use of more basal rates were predictive of good diabetes control in children using CSII. Decisions regarding which pediatric patients are most appropriate for CSII must continue to be individualized.
| Original language | English |
|---|---|
| Pages (from-to) | 217-221 |
| Number of pages | 5 |
| Journal | Diabetes Research and Clinical Practice |
| Volume | 74 |
| Issue number | 3 |
| DOIs | |
| State | Published - Dec 2006 |
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Keywords
- Children and adolescents
- Glycemic control
- Insulin pump therapy
- Type 1 diabetes
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
Cite this
Predictors of glycemic control on insulin pump therapy in children and adolescents with type I diabetes. / Nabhan, Zeina; Rardin, Laura; Meier, Jill; Eugster, Erica; DiMeglio, Linda.
In: Diabetes Research and Clinical Practice, Vol. 74, No. 3, 12.2006, p. 217-221.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Predictors of glycemic control on insulin pump therapy in children and adolescents with type I diabetes
AU - Nabhan, Zeina
AU - Rardin, Laura
AU - Meier, Jill
AU - Eugster, Erica
AU - DiMeglio, Linda
PY - 2006/12
Y1 - 2006/12
N2 - Objective: To determine variables predictive of glycemic control in a large population of pediatric patients with type 1 diabetes on continuous subcutaneous insulin infusion (CSII). Methods: Charts of patients on CSII for ≥1 year were reviewed. "Good" control was a priori defined as HbA1c ≤9% in patients under 12 years of age, and ≤8% in patients over 12 years. Results: Ninety-three patients were identified (57 girls and 36 boys). Their mean age at pump start was 11.6 ± 3.1 years with duration of diabetes of 4.7 ± 3.1 years. Average time on pump therapy was 2.4 ± 0.8 years. HbA1C decreased from 8.7 ± 0.9% prior to pump therapy to 8.3 ± 0.6% while on CSII (p < 0.01). Despite analysis of a large number of possible predictors, only number of basal rates (4.4 versus 3.4) and younger age (10.0 years versus 13.1 years) correlated with good control. Conclusion: Only younger age and use of more basal rates were predictive of good diabetes control in children using CSII. Decisions regarding which pediatric patients are most appropriate for CSII must continue to be individualized.
AB - Objective: To determine variables predictive of glycemic control in a large population of pediatric patients with type 1 diabetes on continuous subcutaneous insulin infusion (CSII). Methods: Charts of patients on CSII for ≥1 year were reviewed. "Good" control was a priori defined as HbA1c ≤9% in patients under 12 years of age, and ≤8% in patients over 12 years. Results: Ninety-three patients were identified (57 girls and 36 boys). Their mean age at pump start was 11.6 ± 3.1 years with duration of diabetes of 4.7 ± 3.1 years. Average time on pump therapy was 2.4 ± 0.8 years. HbA1C decreased from 8.7 ± 0.9% prior to pump therapy to 8.3 ± 0.6% while on CSII (p < 0.01). Despite analysis of a large number of possible predictors, only number of basal rates (4.4 versus 3.4) and younger age (10.0 years versus 13.1 years) correlated with good control. Conclusion: Only younger age and use of more basal rates were predictive of good diabetes control in children using CSII. Decisions regarding which pediatric patients are most appropriate for CSII must continue to be individualized.
KW - Children and adolescents
KW - Glycemic control
KW - Insulin pump therapy
KW - Type 1 diabetes
UR - http://www.scopus.com/inward/record.url?scp=33750024231&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33750024231&partnerID=8YFLogxK
U2 - 10.1016/j.diabres.2006.03.020
DO - 10.1016/j.diabres.2006.03.020
M3 - Article
C2 - 16704885
AN - SCOPUS:33750024231
VL - 74
SP - 217
EP - 221
JO - Diabetes Research and Clinical Practice
JF - Diabetes Research and Clinical Practice
SN - 0168-8227
IS - 3
ER -