Predictors of glycemic control on insulin pump therapy in children and adolescents with type I diabetes

Zeina Nabhan, Laura Rardin, Jill Meier, Erica Eugster, Linda DiMeglio

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Objective: To determine variables predictive of glycemic control in a large population of pediatric patients with type 1 diabetes on continuous subcutaneous insulin infusion (CSII). Methods: Charts of patients on CSII for ≥1 year were reviewed. "Good" control was a priori defined as HbA1c ≤9% in patients under 12 years of age, and ≤8% in patients over 12 years. Results: Ninety-three patients were identified (57 girls and 36 boys). Their mean age at pump start was 11.6 ± 3.1 years with duration of diabetes of 4.7 ± 3.1 years. Average time on pump therapy was 2.4 ± 0.8 years. HbA1C decreased from 8.7 ± 0.9% prior to pump therapy to 8.3 ± 0.6% while on CSII (p < 0.01). Despite analysis of a large number of possible predictors, only number of basal rates (4.4 versus 3.4) and younger age (10.0 years versus 13.1 years) correlated with good control. Conclusion: Only younger age and use of more basal rates were predictive of good diabetes control in children using CSII. Decisions regarding which pediatric patients are most appropriate for CSII must continue to be individualized.

Original languageEnglish
Pages (from-to)217-221
Number of pages5
JournalDiabetes Research and Clinical Practice
Volume74
Issue number3
DOIs
StatePublished - Dec 2006

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Subcutaneous Infusions
Type 1 Diabetes Mellitus
Insulin
Therapeutics
Pediatrics
Population

Keywords

  • Children and adolescents
  • Glycemic control
  • Insulin pump therapy
  • Type 1 diabetes

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Predictors of glycemic control on insulin pump therapy in children and adolescents with type I diabetes. / Nabhan, Zeina; Rardin, Laura; Meier, Jill; Eugster, Erica; DiMeglio, Linda.

In: Diabetes Research and Clinical Practice, Vol. 74, No. 3, 12.2006, p. 217-221.

Research output: Contribution to journalArticle

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