Predictors of intellectual performance in adults with intractable temporal lobe epilepsy

Guila Glosser, Lynne C. Cole, Jacqueline A. French, Andrew Saykin, Michael R. Sperling

Research output: Contribution to journalArticle

54 Citations (Scopus)

Abstract

The relationships of medical, developmental, social, and familial variables to intellectual performances (IQ scores) were assessed in a sample of 242 adult patients with intractable lateralized temporal lobe epilepsy. Lower IQ scores were associated with low patient and parent education. In addition to the significant contributions of nonneurological social and familial factors to IQ, early age at onset of regular seizures and presence of primary neurological dysfunction in the left cerebral hemisphere were also both independently related to lower IQ. The obtained results suggest that the occurrence of regular seizures during a critical period in early childhood neural maturation poses the greatest risk to cognitive development in the epilepsy population. Total duration of seizures, history of severe convulsive episodes, and the occurrence of another nonepileptic neurological problem in early childhood do not contribute significantly to delayed cognitive development.

Original languageEnglish (US)
Pages (from-to)252-259
Number of pages8
JournalJournal of the International Neuropsychological Society
Volume3
Issue number3
StatePublished - May 1997
Externally publishedYes

Fingerprint

Temporal Lobe Epilepsy
Seizures
Cerebrum
Patient Education
Age of Onset
Epilepsy
Population
Drug Resistant Epilepsy

Keywords

  • Epilepsy patients
  • Intelligence in temporal lobe epilepsy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychiatry and Mental health
  • Neuroscience(all)
  • Psychology(all)

Cite this

Predictors of intellectual performance in adults with intractable temporal lobe epilepsy. / Glosser, Guila; Cole, Lynne C.; French, Jacqueline A.; Saykin, Andrew; Sperling, Michael R.

In: Journal of the International Neuropsychological Society, Vol. 3, No. 3, 05.1997, p. 252-259.

Research output: Contribution to journalArticle

Glosser, Guila ; Cole, Lynne C. ; French, Jacqueline A. ; Saykin, Andrew ; Sperling, Michael R. / Predictors of intellectual performance in adults with intractable temporal lobe epilepsy. In: Journal of the International Neuropsychological Society. 1997 ; Vol. 3, No. 3. pp. 252-259.
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