Predictors of pathologic progression on biopsy among men on active surveillance for localized prostate cancer: The value of the pattern of surveillance biopsies

K. Clinton Cary, Janet E. Cowan, Melissa Sanford, Katsuto Shinohara, Nannette Perez, June M. Chan, Maxwell V. Meng, Peter R. Carroll

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Background A better understanding of the independent predictors of disease progression for prostate cancer (PCa) patients is needed to improve the selection of ideal candidates for active surveillance (AS) and refine the surveillance regimen. Objective To examine the association of clinical and pathologic characteristics, as well as patterns of surveillance biopsy results, with the risk of progression in men on AS. Design, setting, and participants The retrospective study consisted of men with PCa who were on AS in the prospectively maintained University of California, San Francisco, institutional database from 1996 to 2011. Strict criteria for AS were prostate-specific antigen (PSA) ≤10 ng/ml, clinical stage T1 or T2, biopsy Gleason grade 6,

Original languageEnglish (US)
Pages (from-to)337-342
Number of pages6
JournalEuropean Urology
Volume66
Issue number2
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Prostatic Neoplasms
Biopsy
San Francisco
Prostate-Specific Antigen
Disease Progression
Retrospective Studies
Databases

Keywords

  • Active surveillance
  • Biopsy
  • Disease progression
  • Pathology
  • Prostatic neoplasms

ASJC Scopus subject areas

  • Urology
  • Medicine(all)

Cite this

Predictors of pathologic progression on biopsy among men on active surveillance for localized prostate cancer : The value of the pattern of surveillance biopsies. / Cary, K. Clinton; Cowan, Janet E.; Sanford, Melissa; Shinohara, Katsuto; Perez, Nannette; Chan, June M.; Meng, Maxwell V.; Carroll, Peter R.

In: European Urology, Vol. 66, No. 2, 2014, p. 337-342.

Research output: Contribution to journalArticle

Cary, K. Clinton ; Cowan, Janet E. ; Sanford, Melissa ; Shinohara, Katsuto ; Perez, Nannette ; Chan, June M. ; Meng, Maxwell V. ; Carroll, Peter R. / Predictors of pathologic progression on biopsy among men on active surveillance for localized prostate cancer : The value of the pattern of surveillance biopsies. In: European Urology. 2014 ; Vol. 66, No. 2. pp. 337-342.
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AU - Meng, Maxwell V.

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