Predictors of short-term treatment response in 66 patients with panic disorder

Donald W. Black, Robert B. Wesner, Janelle Gabel, Wayne Bowers, Patrick Monahan

Research output: Contribution to journalArticlepeer-review

43 Scopus citations


Short-term treatment response in panic disorder was studies in 66 subjects who had completed 3 weeks of treatment with fluvoxamine (n = 23), cognitive therapy (n = 20), or placebo (n = 23). Clinical and self-rated assessments were gathered at baseline, during, and after treatment. Using multiple logistic regression, treatment with fluvoxamine, a low panic attack severity score, and absence of a comorbid personality disorder were identified as significant predictors of recovery. Personality disorder was an important negative predictor to outcome with cognitive therapy. The results support the efficacy of fluvoxamine, and show that patients with low symptom severity and a normal personality respond well to treatment.

Original languageEnglish (US)
Pages (from-to)233-241
Number of pages9
JournalJournal of Affective Disorders
Issue number4
StatePublished - Apr 1994
Externally publishedYes


  • Panic disorder
  • Short-term treatment response

ASJC Scopus subject areas

  • Clinical Psychology
  • Psychiatry and Mental health

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