Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International Clinical Registry and Genetic Repository

Joy Wan, Jack Steiner, Eulalia Baselga, Francine Blei, Maria Cordisco, Maria C. Garzon, Deborah S. Goddard, Anita Haggstrom, Alfons Krol, Ilona J. Frieden, Denise Metry, Kimberly D. Morel, Judith M.A. Verhagen, Orli Wargon, Beth A. Drolet, Dawn H. Siegel

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The cause of PHACE syndrome is unknown. In a study of 218 patients, we examined potential prenatal risk factors for PHACE syndrome. Rates of pre-eclampsia and placenta previa in affected individuals were significantly greater than in the general population. No significant risk factor differences were detected between male and female subjects.

Original languageEnglish (US)
Pages (from-to)275-279
Number of pages5
JournalJournal of Pediatrics
Volume190
DOIs
StatePublished - Nov 2017

Keywords

  • disease pathogenesis
  • hemangioma
  • perinatal risk factors

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Wan, J., Steiner, J., Baselga, E., Blei, F., Cordisco, M., Garzon, M. C., Goddard, D. S., Haggstrom, A., Krol, A., Frieden, I. J., Metry, D., Morel, K. D., Verhagen, J. M. A., Wargon, O., Drolet, B. A., & Siegel, D. H. (2017). Prenatal Risk Factors for PHACE Syndrome: A Study Using the PHACE Syndrome International Clinical Registry and Genetic Repository. Journal of Pediatrics, 190, 275-279. https://doi.org/10.1016/j.jpeds.2017.06.055