Preneoplastic non-papillary lesions and conditions of the urinary bladder

An update based on the ancona international consultation

Antonio Lopez-Beltran, Liang Cheng, Lennart Andersson, Maurizio Brausi, Anna De Matteis, Rodolfo Montironi, Isabell Sesterhenn, Theodorus Van der Kwast, Catherine Mazerolles

Research output: Contribution to journalArticle

71 Citations (Scopus)

Abstract

Background and aims: This paper summarizes the work done by the members of the Committee no. 2 at the International Consultation on the Diagnosis of Non-Invasive Urothelial Neoplasms held in Ancona, Italy (11-12 May 2001). The committee members discussed and reached consensus regarding the optimal contemporary diagnosis and classification of the preneoplastic non-papillary lesions of the urothelium. An important objective was to promote a precise terminology and to use it consistently in daily practice in pathology and urology. Results and conclusions: The result of the meeting is represented by a refined classification of the non- papillary intraepithelial lesions and conditions of the urothelium. This classification includes epithelial abnormalities (reactive urothelial atypia and flat urothelial hyperplasia), presumed preneoplastic lesions and conditions (keratinizing squamous and glandular metaplasia, and malignancy-associated cellular changes), as well as preneoplastic (dysplasia) and neoplastic non-invasive (carcinoma in situ) lesions. Each of these lesions is defined with strict morphological criteria in order to provide more accurate information to urologists in managing patients.

Original languageEnglish
Pages (from-to)3-11
Number of pages9
JournalVirchows Archiv
Volume440
Issue number1
DOIs
StatePublished - 2002

Fingerprint

Committee Membership
Urothelium
Urinary Bladder
Referral and Consultation
Precancerous Conditions
Carcinoma in Situ
Metaplasia
Urology
Terminology
Italy
Hyperplasia
Neoplasms
Pathology
Urologists

Keywords

  • Carcinoma in situ
  • Flat hyperplasia
  • Reactive changes
  • Urothelial dysplasia
  • Urothelial metaplasia
  • Urothelium

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Preneoplastic non-papillary lesions and conditions of the urinary bladder : An update based on the ancona international consultation. / Lopez-Beltran, Antonio; Cheng, Liang; Andersson, Lennart; Brausi, Maurizio; De Matteis, Anna; Montironi, Rodolfo; Sesterhenn, Isabell; Van der Kwast, Theodorus; Mazerolles, Catherine.

In: Virchows Archiv, Vol. 440, No. 1, 2002, p. 3-11.

Research output: Contribution to journalArticle

Lopez-Beltran, A, Cheng, L, Andersson, L, Brausi, M, De Matteis, A, Montironi, R, Sesterhenn, I, Van der Kwast, T & Mazerolles, C 2002, 'Preneoplastic non-papillary lesions and conditions of the urinary bladder: An update based on the ancona international consultation', Virchows Archiv, vol. 440, no. 1, pp. 3-11. https://doi.org/10.1007/s00428-001-0577-6
Lopez-Beltran, Antonio ; Cheng, Liang ; Andersson, Lennart ; Brausi, Maurizio ; De Matteis, Anna ; Montironi, Rodolfo ; Sesterhenn, Isabell ; Van der Kwast, Theodorus ; Mazerolles, Catherine. / Preneoplastic non-papillary lesions and conditions of the urinary bladder : An update based on the ancona international consultation. In: Virchows Archiv. 2002 ; Vol. 440, No. 1. pp. 3-11.
@article{d04a790f5a9a4f739b6497dba879f99f,
title = "Preneoplastic non-papillary lesions and conditions of the urinary bladder: An update based on the ancona international consultation",
abstract = "Background and aims: This paper summarizes the work done by the members of the Committee no. 2 at the International Consultation on the Diagnosis of Non-Invasive Urothelial Neoplasms held in Ancona, Italy (11-12 May 2001). The committee members discussed and reached consensus regarding the optimal contemporary diagnosis and classification of the preneoplastic non-papillary lesions of the urothelium. An important objective was to promote a precise terminology and to use it consistently in daily practice in pathology and urology. Results and conclusions: The result of the meeting is represented by a refined classification of the non- papillary intraepithelial lesions and conditions of the urothelium. This classification includes epithelial abnormalities (reactive urothelial atypia and flat urothelial hyperplasia), presumed preneoplastic lesions and conditions (keratinizing squamous and glandular metaplasia, and malignancy-associated cellular changes), as well as preneoplastic (dysplasia) and neoplastic non-invasive (carcinoma in situ) lesions. Each of these lesions is defined with strict morphological criteria in order to provide more accurate information to urologists in managing patients.",
keywords = "Carcinoma in situ, Flat hyperplasia, Reactive changes, Urothelial dysplasia, Urothelial metaplasia, Urothelium",
author = "Antonio Lopez-Beltran and Liang Cheng and Lennart Andersson and Maurizio Brausi and {De Matteis}, Anna and Rodolfo Montironi and Isabell Sesterhenn and {Van der Kwast}, Theodorus and Catherine Mazerolles",
year = "2002",
doi = "10.1007/s00428-001-0577-6",
language = "English",
volume = "440",
pages = "3--11",
journal = "Virchows Archiv",
issn = "0945-6317",
publisher = "Springer Verlag",
number = "1",

}

TY - JOUR

T1 - Preneoplastic non-papillary lesions and conditions of the urinary bladder

T2 - An update based on the ancona international consultation

AU - Lopez-Beltran, Antonio

AU - Cheng, Liang

AU - Andersson, Lennart

AU - Brausi, Maurizio

AU - De Matteis, Anna

AU - Montironi, Rodolfo

AU - Sesterhenn, Isabell

AU - Van der Kwast, Theodorus

AU - Mazerolles, Catherine

PY - 2002

Y1 - 2002

N2 - Background and aims: This paper summarizes the work done by the members of the Committee no. 2 at the International Consultation on the Diagnosis of Non-Invasive Urothelial Neoplasms held in Ancona, Italy (11-12 May 2001). The committee members discussed and reached consensus regarding the optimal contemporary diagnosis and classification of the preneoplastic non-papillary lesions of the urothelium. An important objective was to promote a precise terminology and to use it consistently in daily practice in pathology and urology. Results and conclusions: The result of the meeting is represented by a refined classification of the non- papillary intraepithelial lesions and conditions of the urothelium. This classification includes epithelial abnormalities (reactive urothelial atypia and flat urothelial hyperplasia), presumed preneoplastic lesions and conditions (keratinizing squamous and glandular metaplasia, and malignancy-associated cellular changes), as well as preneoplastic (dysplasia) and neoplastic non-invasive (carcinoma in situ) lesions. Each of these lesions is defined with strict morphological criteria in order to provide more accurate information to urologists in managing patients.

AB - Background and aims: This paper summarizes the work done by the members of the Committee no. 2 at the International Consultation on the Diagnosis of Non-Invasive Urothelial Neoplasms held in Ancona, Italy (11-12 May 2001). The committee members discussed and reached consensus regarding the optimal contemporary diagnosis and classification of the preneoplastic non-papillary lesions of the urothelium. An important objective was to promote a precise terminology and to use it consistently in daily practice in pathology and urology. Results and conclusions: The result of the meeting is represented by a refined classification of the non- papillary intraepithelial lesions and conditions of the urothelium. This classification includes epithelial abnormalities (reactive urothelial atypia and flat urothelial hyperplasia), presumed preneoplastic lesions and conditions (keratinizing squamous and glandular metaplasia, and malignancy-associated cellular changes), as well as preneoplastic (dysplasia) and neoplastic non-invasive (carcinoma in situ) lesions. Each of these lesions is defined with strict morphological criteria in order to provide more accurate information to urologists in managing patients.

KW - Carcinoma in situ

KW - Flat hyperplasia

KW - Reactive changes

KW - Urothelial dysplasia

KW - Urothelial metaplasia

KW - Urothelium

UR - http://www.scopus.com/inward/record.url?scp=0036166535&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036166535&partnerID=8YFLogxK

U2 - 10.1007/s00428-001-0577-6

DO - 10.1007/s00428-001-0577-6

M3 - Article

VL - 440

SP - 3

EP - 11

JO - Virchows Archiv

JF - Virchows Archiv

SN - 0945-6317

IS - 1

ER -