Presenting symptoms of nonerosive and erosive esophagitis in pediatric patients

Sandeep K. Gupta, Eric Hassall, Yi Lin Chiu, Fouad Amer, Melvin B. Heyman

Research output: Contribution to journalArticle

53 Scopus citations


Children and adolescents with symptomatic gastroesophageal reflux disease (GERD) and erosive esophagitis (EE) of grade ≥2 (n=45) or nonerosive esophagitis (NEE) (n=45) were assessed to determine the relationship between presenting symptoms, esophagitis severity, and patient age. Overall, regurgitation/vomiting, abdominal pain, and cough were the most frequent symptoms. The prevalence and severity of anorexia/feed refusal was significantly greater in EE versus NEE children; this symptom was also significantly more prevalent in younger (1-5 years) children (both NEE and EE groups) compared to older children. Cough was significantly less severe in NEE adolescents than in younger children. Cough, anorexia/feed refusal, and regurgitation/vomiting were more severe and heartburn was less severe in EE children aged 1-5 years compared with older patients. In conclusion, GERD in children manifests differently than that in adults and symptoms vary with patient age. Symptoms were not predictive of presence or lack of mucosal damage.

Original languageEnglish (US)
Pages (from-to)858-863
Number of pages6
JournalDigestive diseases and sciences
Issue number5
StatePublished - May 1 2006


  • Abdominal pain
  • Adolescents
  • Children
  • Cough
  • Erosive esophagitis
  • Feeding problems
  • Gastroesophageal reflux disease
  • Nonerosive reflux disease

ASJC Scopus subject areas

  • Gastroenterology

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