Preterm birth in the first pregnancy and risk of neonatal death in the second pregnancy: A propensity score-weighted matching approach

V. E. Whiteman, E. M. August, M. Mogos, E. Naik, M. Garba, E. Sanchez, H. E. Weldeselasse, H. M. Salihu

Research output: Contribution to journalArticle

Abstract

The study purpose was to assess the relationship between various grades of preterm birth (moderate preterm: 33-36 weeks; severe preterm: 27-32 weeks; extreme preterm: ≤ 26 weeks) in the first pregnancy and neonatal mortality (death within 28 days of birth; early: 0-7 days; late: 8-28 days) in the second pregnancy. Using the Missouri maternally-linked dataset (1989-2005), a population-based, retrospective cohort analysis with propensity score-weighted matching was conducted on mothers with two consecutive singleton live births (n = 310,653 women). Women with a prior preterm birth were more likely to subsequently experience neonatal death. The odds increased in a dose-dependent pattern with ascending severity of the preterm event in the first pregnancy (moderate preterm: AOR = 1.32; 95% CI: 1.10-1.60; severe preterm: AOR = 2.62; 95% CI: 2.01-3.41; extreme preterm: AOR = 5.84; 95% CI: 4.28-7.97; p value for trend <0.001). However, the pathway for the relationship between prior preterm birth and subsequent neonatal mortality may be the recurrence of preterm birth.

Original languageEnglish (US)
Pages (from-to)30-36
Number of pages7
JournalJournal of Obstetrics and Gynaecology
Volume35
Issue number1
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

Fingerprint

Propensity Score
Premature Birth
Pregnancy
Infant Mortality
Live Birth
Cohort Studies
Mothers
Parturition
Recurrence
Perinatal Death
Population

Keywords

  • Birth outcomes
  • Neonatal mortality
  • Pregnancy
  • Preterm birth

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Preterm birth in the first pregnancy and risk of neonatal death in the second pregnancy : A propensity score-weighted matching approach. / Whiteman, V. E.; August, E. M.; Mogos, M.; Naik, E.; Garba, M.; Sanchez, E.; Weldeselasse, H. E.; Salihu, H. M.

In: Journal of Obstetrics and Gynaecology, Vol. 35, No. 1, 01.01.2015, p. 30-36.

Research output: Contribution to journalArticle

Whiteman, V. E. ; August, E. M. ; Mogos, M. ; Naik, E. ; Garba, M. ; Sanchez, E. ; Weldeselasse, H. E. ; Salihu, H. M. / Preterm birth in the first pregnancy and risk of neonatal death in the second pregnancy : A propensity score-weighted matching approach. In: Journal of Obstetrics and Gynaecology. 2015 ; Vol. 35, No. 1. pp. 30-36.
@article{6d3ffb5a332a4e68b982c5c33d437ff0,
title = "Preterm birth in the first pregnancy and risk of neonatal death in the second pregnancy: A propensity score-weighted matching approach",
abstract = "The study purpose was to assess the relationship between various grades of preterm birth (moderate preterm: 33-36 weeks; severe preterm: 27-32 weeks; extreme preterm: ≤ 26 weeks) in the first pregnancy and neonatal mortality (death within 28 days of birth; early: 0-7 days; late: 8-28 days) in the second pregnancy. Using the Missouri maternally-linked dataset (1989-2005), a population-based, retrospective cohort analysis with propensity score-weighted matching was conducted on mothers with two consecutive singleton live births (n = 310,653 women). Women with a prior preterm birth were more likely to subsequently experience neonatal death. The odds increased in a dose-dependent pattern with ascending severity of the preterm event in the first pregnancy (moderate preterm: AOR = 1.32; 95{\%} CI: 1.10-1.60; severe preterm: AOR = 2.62; 95{\%} CI: 2.01-3.41; extreme preterm: AOR = 5.84; 95{\%} CI: 4.28-7.97; p value for trend <0.001). However, the pathway for the relationship between prior preterm birth and subsequent neonatal mortality may be the recurrence of preterm birth.",
keywords = "Birth outcomes, Neonatal mortality, Pregnancy, Preterm birth",
author = "Whiteman, {V. E.} and August, {E. M.} and M. Mogos and E. Naik and M. Garba and E. Sanchez and Weldeselasse, {H. E.} and Salihu, {H. M.}",
year = "2015",
month = "1",
day = "1",
doi = "10.3109/01443615.2014.937328",
language = "English (US)",
volume = "35",
pages = "30--36",
journal = "Journal of Obstetrics and Gynaecology",
issn = "0144-3615",
publisher = "Informa Healthcare",
number = "1",

}

TY - JOUR

T1 - Preterm birth in the first pregnancy and risk of neonatal death in the second pregnancy

T2 - A propensity score-weighted matching approach

AU - Whiteman, V. E.

AU - August, E. M.

AU - Mogos, M.

AU - Naik, E.

AU - Garba, M.

AU - Sanchez, E.

AU - Weldeselasse, H. E.

AU - Salihu, H. M.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - The study purpose was to assess the relationship between various grades of preterm birth (moderate preterm: 33-36 weeks; severe preterm: 27-32 weeks; extreme preterm: ≤ 26 weeks) in the first pregnancy and neonatal mortality (death within 28 days of birth; early: 0-7 days; late: 8-28 days) in the second pregnancy. Using the Missouri maternally-linked dataset (1989-2005), a population-based, retrospective cohort analysis with propensity score-weighted matching was conducted on mothers with two consecutive singleton live births (n = 310,653 women). Women with a prior preterm birth were more likely to subsequently experience neonatal death. The odds increased in a dose-dependent pattern with ascending severity of the preterm event in the first pregnancy (moderate preterm: AOR = 1.32; 95% CI: 1.10-1.60; severe preterm: AOR = 2.62; 95% CI: 2.01-3.41; extreme preterm: AOR = 5.84; 95% CI: 4.28-7.97; p value for trend <0.001). However, the pathway for the relationship between prior preterm birth and subsequent neonatal mortality may be the recurrence of preterm birth.

AB - The study purpose was to assess the relationship between various grades of preterm birth (moderate preterm: 33-36 weeks; severe preterm: 27-32 weeks; extreme preterm: ≤ 26 weeks) in the first pregnancy and neonatal mortality (death within 28 days of birth; early: 0-7 days; late: 8-28 days) in the second pregnancy. Using the Missouri maternally-linked dataset (1989-2005), a population-based, retrospective cohort analysis with propensity score-weighted matching was conducted on mothers with two consecutive singleton live births (n = 310,653 women). Women with a prior preterm birth were more likely to subsequently experience neonatal death. The odds increased in a dose-dependent pattern with ascending severity of the preterm event in the first pregnancy (moderate preterm: AOR = 1.32; 95% CI: 1.10-1.60; severe preterm: AOR = 2.62; 95% CI: 2.01-3.41; extreme preterm: AOR = 5.84; 95% CI: 4.28-7.97; p value for trend <0.001). However, the pathway for the relationship between prior preterm birth and subsequent neonatal mortality may be the recurrence of preterm birth.

KW - Birth outcomes

KW - Neonatal mortality

KW - Pregnancy

KW - Preterm birth

UR - http://www.scopus.com/inward/record.url?scp=84919460356&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84919460356&partnerID=8YFLogxK

U2 - 10.3109/01443615.2014.937328

DO - 10.3109/01443615.2014.937328

M3 - Article

AN - SCOPUS:84919460356

VL - 35

SP - 30

EP - 36

JO - Journal of Obstetrics and Gynaecology

JF - Journal of Obstetrics and Gynaecology

SN - 0144-3615

IS - 1

ER -