Prevalence of Alzheimer's disease and dementia in two communities: Nigerian Africans and African Americans

Hugh C. Hendrie, Benjamin O. Osuntokun, Kathleen S. Hall, Adesola O. Ogunniyi, Siu L. Hui, Frederick W. Unverzagt, Oyewusi Gureje, Cynthia A. Rodenberg, Olusegun Baiyewu, Beverly S. Musick, Abiodun Adeyinka, Martin R. Farlow, S. O. Oluwole, C. Andrew Class, O. Komolafe, Allison Brashear, Vicki Burdine

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Abstract

Objective: This article reports on a prevalence study of dementia and Alzheimer's disease among two groups of subjects with the same ethnic background but widely differing environments. Method: The study was conducted among residents aged 65 years and older in two communities: Yorubas (N=2,494) living in Ibadan, Nigeria, and African Americans (N=2,212 in the community and N=106 in nursing homes) living in Indianapolis, Indiana. The study design consisted of a screening stage followed by a clinical assessment stage for selected subjects on the basis of their performance on the screening tests. Results: The age-adjusted prevalence rates of dementia (2.29%) and Alzheimer's disease (1.41%) in the Ibadan sample were significantly lower than those in the Indianapolis sample, both in the community-dwelling subjects alone [4.82%, and 3.69%, respectively) and in the combined nursing home and community samples (8.24% and 6.24%, respectively). The prevalence rates of dementia and Alzheimer's disease increased consistently with advancing age in both study groups. Conclusions: To the authors' knowledge, this is the first study, using the same research method at the two sites, to report significant differences in rates of dementia and Alzheimer's disease in two different communities with similar ethnic origins.

Original languageEnglish (US)
Pages (from-to)1485-1492
Number of pages8
JournalAmerican Journal of Psychiatry
Volume152
Issue number10
DOIs
StatePublished - Oct 1995

ASJC Scopus subject areas

  • Psychiatry and Mental health

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    Hendrie, H. C., Osuntokun, B. O., Hall, K. S., Ogunniyi, A. O., Hui, S. L., Unverzagt, F. W., Gureje, O., Rodenberg, C. A., Baiyewu, O., Musick, B. S., Adeyinka, A., Farlow, M. R., Oluwole, S. O., Class, C. A., Komolafe, O., Brashear, A., & Burdine, V. (1995). Prevalence of Alzheimer's disease and dementia in two communities: Nigerian Africans and African Americans. American Journal of Psychiatry, 152(10), 1485-1492. https://doi.org/10.1176/ajp.152.10.1485