Prevalence of Glaucoma: The Beaver Dam Eye Study

Barbara E.K. Klein, Ronald Klein, William E. Sponsel, Todd Franke, Louis B. Cantor, James Martone, Mitchell J. Menage

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Abstract

Purpose: The purpose of this study is to determine the prevalence of glaucoma in the population participating in the Beaver Dam Eye Study (n = 4926). Methods: All subjects were examined according to standard protocols, which included applanation tonometry, examination of the anterior chamber, perimetry, grading of fundus photographs of the optic disc, and a medical history interview. Visual field, cup-to-disc ratio, and intraocular pressure (IOP) criteria were used to define the presence of open-angle glaucoma. Definite open-angle glaucoma was defined by the presence of any two or all three of the following: abnormal visual field, large or asymmetric cupto-disc ratio, high IOP. Results: The overall prevalence of definite open-angle glaucoma was 2.1 %. The prevalence increased with age from 0.9% in people 43 to 54 years of age to 4.7% in people 75 years of age or older. There was no significant effect of sex after adjusting for age. Of the 104 cases of definite open-angle glaucoma, 33 had IOPs less than 22 mmHg in the involved eye. Hemorrhage on the optic disc was found in 46 people; 2 of these had glaucoma. Narrow-angle glaucoma was rare, with two definite cases in the population. Conclusion: The prevalence of open-angle glaucoma in Beaver Dam is similar to that in other white populations. Findings from this study re-emphasize the notion that estimates of glaucoma prevalence should be based on assessing multiple risk indicators.

Original languageEnglish (US)
Pages (from-to)1499-1504
Number of pages6
JournalOphthalmology
Volume99
Issue number10
DOIs
StatePublished - Jan 1 1992

ASJC Scopus subject areas

  • Ophthalmology

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    Klein, B. E. K., Klein, R., Sponsel, W. E., Franke, T., Cantor, L. B., Martone, J., & Menage, M. J. (1992). Prevalence of Glaucoma: The Beaver Dam Eye Study. Ophthalmology, 99(10), 1499-1504. https://doi.org/10.1016/S0161-6420(92)31774-9