Prevalence of Open-Angle Glaucoma in Greece: The Thessaloniki Eye Study

Fotis Topouzis, M. Roy Wilson, Alon Harris, Eleftherios Anastasopoulos, Fei Yu, Leonidas Mavroudis, Theofanis Pappas, Archimidis Koskosas, Anne L. Coleman

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

Purpose: To estimate the prevalence of open-angle glaucoma (OAG) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece. Design: Cross-sectional population-based study. Methods: Subjects randomly identified from municipality registers in Thessaloniki underwent a complete ophthalmologic examination. Glaucoma was defined in two ways. Definition 1 was based on the presence of both glaucomatous optic disk and confirmed glaucomatous visual field defect. Subjects also were classified as having glaucoma when the clinical judgment was strongly in favor of the presence of glaucoma even though the strict criteria were not fulfilled (definition 2). Results: Of the 3,617 eligible subjects, 2,554 (71%) participated. The prevalence of OAG was 3.8% and 5.5% by definitions 1 and 2, respectively. The prevalence of primary OAG was 2.7% and 3.8% by definitions 1 and 2, respectively, and the prevalence of pseudoexfoliation glaucoma (PEXG) was 1.1% and 1.7% by definitions 1 and 2, respectively. Pseudoexfoliation was present in 11.9% of participants, whereas 15.2% among those with pseudoexfoliation had PEXG. Conclusions: The prevalence of OAG in the Thessaloniki Eye Study (TES) is similar or slightly higher compared with other population-based studies in White persons. The overall slightly higher prevalence of OAG in the TES compared with other studies may be attributed to the high prevalence of PEXG in the TES.

Original languageEnglish (US)
Pages (from-to)511-519.e1
JournalAmerican Journal of Ophthalmology
Volume144
Issue number4
DOIs
StatePublished - Oct 2007

Fingerprint

Open Angle Glaucoma
Greece
Glaucoma
Population
Optic Disk
Visual Fields

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Topouzis, F., Wilson, M. R., Harris, A., Anastasopoulos, E., Yu, F., Mavroudis, L., ... Coleman, A. L. (2007). Prevalence of Open-Angle Glaucoma in Greece: The Thessaloniki Eye Study. American Journal of Ophthalmology, 144(4), 511-519.e1. https://doi.org/10.1016/j.ajo.2007.06.029

Prevalence of Open-Angle Glaucoma in Greece : The Thessaloniki Eye Study. / Topouzis, Fotis; Wilson, M. Roy; Harris, Alon; Anastasopoulos, Eleftherios; Yu, Fei; Mavroudis, Leonidas; Pappas, Theofanis; Koskosas, Archimidis; Coleman, Anne L.

In: American Journal of Ophthalmology, Vol. 144, No. 4, 10.2007, p. 511-519.e1.

Research output: Contribution to journalArticle

Topouzis, F, Wilson, MR, Harris, A, Anastasopoulos, E, Yu, F, Mavroudis, L, Pappas, T, Koskosas, A & Coleman, AL 2007, 'Prevalence of Open-Angle Glaucoma in Greece: The Thessaloniki Eye Study', American Journal of Ophthalmology, vol. 144, no. 4, pp. 511-519.e1. https://doi.org/10.1016/j.ajo.2007.06.029
Topouzis, Fotis ; Wilson, M. Roy ; Harris, Alon ; Anastasopoulos, Eleftherios ; Yu, Fei ; Mavroudis, Leonidas ; Pappas, Theofanis ; Koskosas, Archimidis ; Coleman, Anne L. / Prevalence of Open-Angle Glaucoma in Greece : The Thessaloniki Eye Study. In: American Journal of Ophthalmology. 2007 ; Vol. 144, No. 4. pp. 511-519.e1.
@article{a5521d3cf14c4ff1b0fba392a7c5e22b,
title = "Prevalence of Open-Angle Glaucoma in Greece: The Thessaloniki Eye Study",
abstract = "Purpose: To estimate the prevalence of open-angle glaucoma (OAG) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece. Design: Cross-sectional population-based study. Methods: Subjects randomly identified from municipality registers in Thessaloniki underwent a complete ophthalmologic examination. Glaucoma was defined in two ways. Definition 1 was based on the presence of both glaucomatous optic disk and confirmed glaucomatous visual field defect. Subjects also were classified as having glaucoma when the clinical judgment was strongly in favor of the presence of glaucoma even though the strict criteria were not fulfilled (definition 2). Results: Of the 3,617 eligible subjects, 2,554 (71{\%}) participated. The prevalence of OAG was 3.8{\%} and 5.5{\%} by definitions 1 and 2, respectively. The prevalence of primary OAG was 2.7{\%} and 3.8{\%} by definitions 1 and 2, respectively, and the prevalence of pseudoexfoliation glaucoma (PEXG) was 1.1{\%} and 1.7{\%} by definitions 1 and 2, respectively. Pseudoexfoliation was present in 11.9{\%} of participants, whereas 15.2{\%} among those with pseudoexfoliation had PEXG. Conclusions: The prevalence of OAG in the Thessaloniki Eye Study (TES) is similar or slightly higher compared with other population-based studies in White persons. The overall slightly higher prevalence of OAG in the TES compared with other studies may be attributed to the high prevalence of PEXG in the TES.",
author = "Fotis Topouzis and Wilson, {M. Roy} and Alon Harris and Eleftherios Anastasopoulos and Fei Yu and Leonidas Mavroudis and Theofanis Pappas and Archimidis Koskosas and Coleman, {Anne L.}",
year = "2007",
month = "10",
doi = "10.1016/j.ajo.2007.06.029",
language = "English (US)",
volume = "144",
pages = "511--519.e1",
journal = "American Journal of Ophthalmology",
issn = "0002-9394",
publisher = "Elsevier USA",
number = "4",

}

TY - JOUR

T1 - Prevalence of Open-Angle Glaucoma in Greece

T2 - The Thessaloniki Eye Study

AU - Topouzis, Fotis

AU - Wilson, M. Roy

AU - Harris, Alon

AU - Anastasopoulos, Eleftherios

AU - Yu, Fei

AU - Mavroudis, Leonidas

AU - Pappas, Theofanis

AU - Koskosas, Archimidis

AU - Coleman, Anne L.

PY - 2007/10

Y1 - 2007/10

N2 - Purpose: To estimate the prevalence of open-angle glaucoma (OAG) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece. Design: Cross-sectional population-based study. Methods: Subjects randomly identified from municipality registers in Thessaloniki underwent a complete ophthalmologic examination. Glaucoma was defined in two ways. Definition 1 was based on the presence of both glaucomatous optic disk and confirmed glaucomatous visual field defect. Subjects also were classified as having glaucoma when the clinical judgment was strongly in favor of the presence of glaucoma even though the strict criteria were not fulfilled (definition 2). Results: Of the 3,617 eligible subjects, 2,554 (71%) participated. The prevalence of OAG was 3.8% and 5.5% by definitions 1 and 2, respectively. The prevalence of primary OAG was 2.7% and 3.8% by definitions 1 and 2, respectively, and the prevalence of pseudoexfoliation glaucoma (PEXG) was 1.1% and 1.7% by definitions 1 and 2, respectively. Pseudoexfoliation was present in 11.9% of participants, whereas 15.2% among those with pseudoexfoliation had PEXG. Conclusions: The prevalence of OAG in the Thessaloniki Eye Study (TES) is similar or slightly higher compared with other population-based studies in White persons. The overall slightly higher prevalence of OAG in the TES compared with other studies may be attributed to the high prevalence of PEXG in the TES.

AB - Purpose: To estimate the prevalence of open-angle glaucoma (OAG) in a population-based sample of subjects 60 years of age or older in Thessaloniki, Greece. Design: Cross-sectional population-based study. Methods: Subjects randomly identified from municipality registers in Thessaloniki underwent a complete ophthalmologic examination. Glaucoma was defined in two ways. Definition 1 was based on the presence of both glaucomatous optic disk and confirmed glaucomatous visual field defect. Subjects also were classified as having glaucoma when the clinical judgment was strongly in favor of the presence of glaucoma even though the strict criteria were not fulfilled (definition 2). Results: Of the 3,617 eligible subjects, 2,554 (71%) participated. The prevalence of OAG was 3.8% and 5.5% by definitions 1 and 2, respectively. The prevalence of primary OAG was 2.7% and 3.8% by definitions 1 and 2, respectively, and the prevalence of pseudoexfoliation glaucoma (PEXG) was 1.1% and 1.7% by definitions 1 and 2, respectively. Pseudoexfoliation was present in 11.9% of participants, whereas 15.2% among those with pseudoexfoliation had PEXG. Conclusions: The prevalence of OAG in the Thessaloniki Eye Study (TES) is similar or slightly higher compared with other population-based studies in White persons. The overall slightly higher prevalence of OAG in the TES compared with other studies may be attributed to the high prevalence of PEXG in the TES.

UR - http://www.scopus.com/inward/record.url?scp=34548750457&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34548750457&partnerID=8YFLogxK

U2 - 10.1016/j.ajo.2007.06.029

DO - 10.1016/j.ajo.2007.06.029

M3 - Article

C2 - 17893012

AN - SCOPUS:34548750457

VL - 144

SP - 511-519.e1

JO - American Journal of Ophthalmology

JF - American Journal of Ophthalmology

SN - 0002-9394

IS - 4

ER -