Prevalence of sleep disturbances in children and adolescents with chronic kidney disease

Ira D. Davis, Larry A. Greenbaum, Debbie Gipson, Lie Ling Wu, Rajiv Sinha, Mina Matsuda-Abedini, Judith L. Emancipator, Jerome C. Lane, Kavita Hodgkins, Corina Nailescu, Gina Marie Barletta, Steven Arora, John D. Mahan, Carol L. Rosen

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Although sleep disorders are common in adults with chronic kidney disease, little is known about the prevalence of sleep problems in children and adolescents with chronic kidney disease and their relationship to healthrelated quality of life measurements. We performed a clinicbased survey of sleep habits and common symptoms of sleep disturbances in 159 school-aged patients with chronic kidney disease. Three patient groups of chronic kidney disease were assessed: group 1, those not on dialysis and not transplanted; group 2, those on dialysis; and group 3, those with a functioning renal allograft. Four symptom domains for sleep disorders were assessed: excessive daytime sleepiness; sleep disordered breathing; restless legs syndrome symptoms; and insufficient sleep. Patients and the parent-proxy also completed the Pediatric Quality of Life Inventory Version 4.0 Generic Core Scales questionnaire. Ninety-three (93) patients (58.5%) had symptoms of a sleep disturbance. The presence of a sleep disturbance correlated with a decrease in health-related quality of life scores that was independent of the chronic kidney disease study group or estimated glomerular filtration rate. We conclude that sleep disturbances are common throughout the spectrum of chronic kidney disease in children and adolescents and are associated with diminished healthrelated quality of life scores.

Original languageEnglish
Pages (from-to)451-459
Number of pages9
JournalPediatric Nephrology
Volume27
Issue number3
DOIs
StatePublished - Mar 2012

Fingerprint

Chronic Renal Insufficiency
Sleep
Quality of Life
Dialysis
Restless Legs Syndrome
Sleep Apnea Syndromes
Proxy
Glomerular Filtration Rate
Habits
Allografts
Pediatrics
Kidney
Equipment and Supplies

Keywords

  • Dialysis
  • Excessive daytime sleepiness
  • Health-related quality of life
  • Renal transplantation
  • Restless legs syndrome
  • Sleep disordered breathing

ASJC Scopus subject areas

  • Nephrology
  • Pediatrics, Perinatology, and Child Health

Cite this

Davis, I. D., Greenbaum, L. A., Gipson, D., Wu, L. L., Sinha, R., Matsuda-Abedini, M., ... Rosen, C. L. (2012). Prevalence of sleep disturbances in children and adolescents with chronic kidney disease. Pediatric Nephrology, 27(3), 451-459. https://doi.org/10.1007/s00467-011-2010-y

Prevalence of sleep disturbances in children and adolescents with chronic kidney disease. / Davis, Ira D.; Greenbaum, Larry A.; Gipson, Debbie; Wu, Lie Ling; Sinha, Rajiv; Matsuda-Abedini, Mina; Emancipator, Judith L.; Lane, Jerome C.; Hodgkins, Kavita; Nailescu, Corina; Barletta, Gina Marie; Arora, Steven; Mahan, John D.; Rosen, Carol L.

In: Pediatric Nephrology, Vol. 27, No. 3, 03.2012, p. 451-459.

Research output: Contribution to journalArticle

Davis, ID, Greenbaum, LA, Gipson, D, Wu, LL, Sinha, R, Matsuda-Abedini, M, Emancipator, JL, Lane, JC, Hodgkins, K, Nailescu, C, Barletta, GM, Arora, S, Mahan, JD & Rosen, CL 2012, 'Prevalence of sleep disturbances in children and adolescents with chronic kidney disease', Pediatric Nephrology, vol. 27, no. 3, pp. 451-459. https://doi.org/10.1007/s00467-011-2010-y
Davis ID, Greenbaum LA, Gipson D, Wu LL, Sinha R, Matsuda-Abedini M et al. Prevalence of sleep disturbances in children and adolescents with chronic kidney disease. Pediatric Nephrology. 2012 Mar;27(3):451-459. https://doi.org/10.1007/s00467-011-2010-y
Davis, Ira D. ; Greenbaum, Larry A. ; Gipson, Debbie ; Wu, Lie Ling ; Sinha, Rajiv ; Matsuda-Abedini, Mina ; Emancipator, Judith L. ; Lane, Jerome C. ; Hodgkins, Kavita ; Nailescu, Corina ; Barletta, Gina Marie ; Arora, Steven ; Mahan, John D. ; Rosen, Carol L. / Prevalence of sleep disturbances in children and adolescents with chronic kidney disease. In: Pediatric Nephrology. 2012 ; Vol. 27, No. 3. pp. 451-459.
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