Prevalence rates for dementia and Alzheimer's disease in African Americans: 1992 versus 2001

Kathleen Hall, Sujuan Gao, Olusegun Baiyewu, Kathleen A. Lane, Oye Gureje, Jianzhao Shen, Adesola Ogunniyi, Jill R. Murrell, Frederick Unverzagt, Jeanne Dickens, Valerie Smith-Gamble, Hugh Hendrie

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Background: This study compares age-specific and overall prevalence rates for dementia and Alzheimer's disease (AD) in two nonoverlapping, population-based cohorts of elderly African Americans in Indianapolis in 2001 and 1992. Methods: We used a two-stage design. The first stage involves the Community Screening Interview for Dementia (CSI-D). The CSI-D scores are grouped into good, intermediate, and poor performance before selection for clinical assessment. Diagnoses were performed using standard criteria in a consensus diagnosis conference; clinicians were blind to performance groups. In 1992, interviewers visited randomly sampled addresses to enroll self-identified African Americans aged ≥65 years. Of 2582 eligible, 2212 enrolled (9.6% refused, and 4.7% were too sick). In 2001, Medicare rolls were used for African Americans aged >70 years. Of 4260 eligible, 1892 (44%) enrolled, 1999 (47%) refused, and the remainder did not participate for other reasons. Results: The overall age-adjusted prevalence rate for dementia at age ≥70 years in 2001 was 7.45% (95 confidence interval [CI], 4.27-10.64), and in the 1992 cohort, this prevalence rate was 6.75% (95% CI, 5.77-7.74). The overall age-adjusted prevalence rate at age ≥70 years for AD in the 2001 cohort was 6.77% (95% CI, 3.65-9.90), and for the 1992 cohort, it was 5.47% (95% CI, 4.51-6.42). Rates for dementia and AD were not significantly different in the two cohorts (dementia, P = .3534; AD, P = .2649). Conclusions: We found no differences in the prevalence rates of dementia and AD between 1992 and 2001, despite significant differences in medical history and medical treatment within these population-based cohorts of African American elderly.

Original languageEnglish
Pages (from-to)227-233
Number of pages7
JournalAlzheimer's and Dementia
Volume5
Issue number3
DOIs
StatePublished - May 2009

Fingerprint

African Americans
Dementia
Alzheimer Disease
Confidence Intervals
Interviews
Medicare
Population

Keywords

  • 1992 vs 2001
  • African Americans
  • Alzheimer's disease
  • Population-based
  • Prevalence rates

ASJC Scopus subject areas

  • Health Policy
  • Epidemiology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience
  • Developmental Neuroscience
  • Clinical Neurology

Cite this

Prevalence rates for dementia and Alzheimer's disease in African Americans : 1992 versus 2001. / Hall, Kathleen; Gao, Sujuan; Baiyewu, Olusegun; Lane, Kathleen A.; Gureje, Oye; Shen, Jianzhao; Ogunniyi, Adesola; Murrell, Jill R.; Unverzagt, Frederick; Dickens, Jeanne; Smith-Gamble, Valerie; Hendrie, Hugh.

In: Alzheimer's and Dementia, Vol. 5, No. 3, 05.2009, p. 227-233.

Research output: Contribution to journalArticle

Hall, K, Gao, S, Baiyewu, O, Lane, KA, Gureje, O, Shen, J, Ogunniyi, A, Murrell, JR, Unverzagt, F, Dickens, J, Smith-Gamble, V & Hendrie, H 2009, 'Prevalence rates for dementia and Alzheimer's disease in African Americans: 1992 versus 2001', Alzheimer's and Dementia, vol. 5, no. 3, pp. 227-233. https://doi.org/10.1016/j.jalz.2009.01.026
Hall, Kathleen ; Gao, Sujuan ; Baiyewu, Olusegun ; Lane, Kathleen A. ; Gureje, Oye ; Shen, Jianzhao ; Ogunniyi, Adesola ; Murrell, Jill R. ; Unverzagt, Frederick ; Dickens, Jeanne ; Smith-Gamble, Valerie ; Hendrie, Hugh. / Prevalence rates for dementia and Alzheimer's disease in African Americans : 1992 versus 2001. In: Alzheimer's and Dementia. 2009 ; Vol. 5, No. 3. pp. 227-233.
@article{6d94f0bf1a234ebbb00ea6ae0e71ada5,
title = "Prevalence rates for dementia and Alzheimer's disease in African Americans: 1992 versus 2001",
abstract = "Background: This study compares age-specific and overall prevalence rates for dementia and Alzheimer's disease (AD) in two nonoverlapping, population-based cohorts of elderly African Americans in Indianapolis in 2001 and 1992. Methods: We used a two-stage design. The first stage involves the Community Screening Interview for Dementia (CSI-D). The CSI-D scores are grouped into good, intermediate, and poor performance before selection for clinical assessment. Diagnoses were performed using standard criteria in a consensus diagnosis conference; clinicians were blind to performance groups. In 1992, interviewers visited randomly sampled addresses to enroll self-identified African Americans aged ≥65 years. Of 2582 eligible, 2212 enrolled (9.6{\%} refused, and 4.7{\%} were too sick). In 2001, Medicare rolls were used for African Americans aged >70 years. Of 4260 eligible, 1892 (44{\%}) enrolled, 1999 (47{\%}) refused, and the remainder did not participate for other reasons. Results: The overall age-adjusted prevalence rate for dementia at age ≥70 years in 2001 was 7.45{\%} (95 confidence interval [CI], 4.27-10.64), and in the 1992 cohort, this prevalence rate was 6.75{\%} (95{\%} CI, 5.77-7.74). The overall age-adjusted prevalence rate at age ≥70 years for AD in the 2001 cohort was 6.77{\%} (95{\%} CI, 3.65-9.90), and for the 1992 cohort, it was 5.47{\%} (95{\%} CI, 4.51-6.42). Rates for dementia and AD were not significantly different in the two cohorts (dementia, P = .3534; AD, P = .2649). Conclusions: We found no differences in the prevalence rates of dementia and AD between 1992 and 2001, despite significant differences in medical history and medical treatment within these population-based cohorts of African American elderly.",
keywords = "1992 vs 2001, African Americans, Alzheimer's disease, Population-based, Prevalence rates",
author = "Kathleen Hall and Sujuan Gao and Olusegun Baiyewu and Lane, {Kathleen A.} and Oye Gureje and Jianzhao Shen and Adesola Ogunniyi and Murrell, {Jill R.} and Frederick Unverzagt and Jeanne Dickens and Valerie Smith-Gamble and Hugh Hendrie",
year = "2009",
month = "5",
doi = "10.1016/j.jalz.2009.01.026",
language = "English",
volume = "5",
pages = "227--233",
journal = "Alzheimer's and Dementia",
issn = "1552-5260",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Prevalence rates for dementia and Alzheimer's disease in African Americans

T2 - 1992 versus 2001

AU - Hall, Kathleen

AU - Gao, Sujuan

AU - Baiyewu, Olusegun

AU - Lane, Kathleen A.

AU - Gureje, Oye

AU - Shen, Jianzhao

AU - Ogunniyi, Adesola

AU - Murrell, Jill R.

AU - Unverzagt, Frederick

AU - Dickens, Jeanne

AU - Smith-Gamble, Valerie

AU - Hendrie, Hugh

PY - 2009/5

Y1 - 2009/5

N2 - Background: This study compares age-specific and overall prevalence rates for dementia and Alzheimer's disease (AD) in two nonoverlapping, population-based cohorts of elderly African Americans in Indianapolis in 2001 and 1992. Methods: We used a two-stage design. The first stage involves the Community Screening Interview for Dementia (CSI-D). The CSI-D scores are grouped into good, intermediate, and poor performance before selection for clinical assessment. Diagnoses were performed using standard criteria in a consensus diagnosis conference; clinicians were blind to performance groups. In 1992, interviewers visited randomly sampled addresses to enroll self-identified African Americans aged ≥65 years. Of 2582 eligible, 2212 enrolled (9.6% refused, and 4.7% were too sick). In 2001, Medicare rolls were used for African Americans aged >70 years. Of 4260 eligible, 1892 (44%) enrolled, 1999 (47%) refused, and the remainder did not participate for other reasons. Results: The overall age-adjusted prevalence rate for dementia at age ≥70 years in 2001 was 7.45% (95 confidence interval [CI], 4.27-10.64), and in the 1992 cohort, this prevalence rate was 6.75% (95% CI, 5.77-7.74). The overall age-adjusted prevalence rate at age ≥70 years for AD in the 2001 cohort was 6.77% (95% CI, 3.65-9.90), and for the 1992 cohort, it was 5.47% (95% CI, 4.51-6.42). Rates for dementia and AD were not significantly different in the two cohorts (dementia, P = .3534; AD, P = .2649). Conclusions: We found no differences in the prevalence rates of dementia and AD between 1992 and 2001, despite significant differences in medical history and medical treatment within these population-based cohorts of African American elderly.

AB - Background: This study compares age-specific and overall prevalence rates for dementia and Alzheimer's disease (AD) in two nonoverlapping, population-based cohorts of elderly African Americans in Indianapolis in 2001 and 1992. Methods: We used a two-stage design. The first stage involves the Community Screening Interview for Dementia (CSI-D). The CSI-D scores are grouped into good, intermediate, and poor performance before selection for clinical assessment. Diagnoses were performed using standard criteria in a consensus diagnosis conference; clinicians were blind to performance groups. In 1992, interviewers visited randomly sampled addresses to enroll self-identified African Americans aged ≥65 years. Of 2582 eligible, 2212 enrolled (9.6% refused, and 4.7% were too sick). In 2001, Medicare rolls were used for African Americans aged >70 years. Of 4260 eligible, 1892 (44%) enrolled, 1999 (47%) refused, and the remainder did not participate for other reasons. Results: The overall age-adjusted prevalence rate for dementia at age ≥70 years in 2001 was 7.45% (95 confidence interval [CI], 4.27-10.64), and in the 1992 cohort, this prevalence rate was 6.75% (95% CI, 5.77-7.74). The overall age-adjusted prevalence rate at age ≥70 years for AD in the 2001 cohort was 6.77% (95% CI, 3.65-9.90), and for the 1992 cohort, it was 5.47% (95% CI, 4.51-6.42). Rates for dementia and AD were not significantly different in the two cohorts (dementia, P = .3534; AD, P = .2649). Conclusions: We found no differences in the prevalence rates of dementia and AD between 1992 and 2001, despite significant differences in medical history and medical treatment within these population-based cohorts of African American elderly.

KW - 1992 vs 2001

KW - African Americans

KW - Alzheimer's disease

KW - Population-based

KW - Prevalence rates

UR - http://www.scopus.com/inward/record.url?scp=65449147828&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=65449147828&partnerID=8YFLogxK

U2 - 10.1016/j.jalz.2009.01.026

DO - 10.1016/j.jalz.2009.01.026

M3 - Article

C2 - 19426950

AN - SCOPUS:65449147828

VL - 5

SP - 227

EP - 233

JO - Alzheimer's and Dementia

JF - Alzheimer's and Dementia

SN - 1552-5260

IS - 3

ER -