Primary Choriocarcinoma of the Bladder: A Case Report and Review of Literature

M. Francesca Monn, Kaitlin R. Jaqua, Richard Bihrle, Liang Cheng

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Abstract

Primary choriocarcinoma of the urinary bladder is a rare entity, and should be distinguished from urothelial carcinoma with trophoblastic differentiation. The leading treatment modalities include surgical extirpation, chemotherapy, and radiation; however, survival remains poor. Herein we describe a rare case of choriocarcinoma of the bladder in a man who presented for evaluation with hematuria and subsequently underwent radical cystectomy with urinary diversion. Diagnosis of extragonadal germ cell tumor was confirmed using fluorescence in situ hybridization identification of isochromosome 12p.

Original languageEnglish (US)
JournalClinical Genitourinary Cancer
DOIs
StateAccepted/In press - Aug 24 2016

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Keywords

  • Bladder choriocarcinoma
  • Cytogenetics/fluorescence in situ hybridization
  • Extragonadal germ cell tumor
  • Isochromosome 12p (i12p)
  • Urothelial carcinoma

ASJC Scopus subject areas

  • Oncology
  • Urology

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