Primary hyperparathyroidism associated with primary hyperaldosteronism

J. B. Ferriss, J. J. Brown, A. M M Cumming, R. Fraser, A. F. Lever, Munro Peacock, J. I. Robertson

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Two patients with both primary hyperparathyroidism and primary hyperaldosteronism are described. Each presented with high blood pressure and a history of renal calculi. Mild hypercalcaemia was associated with raised plasma parathyroid hormone concentrations and a parathyroid adenoma was excised from each. Both patients also had hypokalaemia, hyperaldosteronism and low plasma renin concentrations. Quadric analysis, adrenal vein plasma aldosterone concentrations, adrenal venography and CT scanning all suggested an adrenal adenoma in each patient; the other patient is unfit for adrenal surgery but her blood pressure and plasma potassium concentration have remained within the normal range during prolonged treatment with either spironolactone or amiloride. Because of this unusual association a search was made for parathyroid hormone excess in patients with primary hyperaldosteronism and for aldosterone excess in primary hyperparathyroidism. None was found.

Original languageEnglish (US)
Pages (from-to)365-370
Number of pages6
JournalActa Endocrinologica
Volume103
Issue number3
StatePublished - 1983
Externally publishedYes

Fingerprint

Hyperaldosteronism
Primary Hyperparathyroidism
Aldosterone
Parathyroid Hormone
Parathyroid Neoplasms
Spironolactone
Kidney Calculi
Hypokalemia
Phlebography
Amiloride
Hypercalcemia
Renin
Adenoma
Veins
Potassium
Reference Values
Blood Pressure
Hypertension

ASJC Scopus subject areas

  • Endocrinology

Cite this

Ferriss, J. B., Brown, J. J., Cumming, A. M. M., Fraser, R., Lever, A. F., Peacock, M., & Robertson, J. I. (1983). Primary hyperparathyroidism associated with primary hyperaldosteronism. Acta Endocrinologica, 103(3), 365-370.

Primary hyperparathyroidism associated with primary hyperaldosteronism. / Ferriss, J. B.; Brown, J. J.; Cumming, A. M M; Fraser, R.; Lever, A. F.; Peacock, Munro; Robertson, J. I.

In: Acta Endocrinologica, Vol. 103, No. 3, 1983, p. 365-370.

Research output: Contribution to journalArticle

Ferriss, JB, Brown, JJ, Cumming, AMM, Fraser, R, Lever, AF, Peacock, M & Robertson, JI 1983, 'Primary hyperparathyroidism associated with primary hyperaldosteronism', Acta Endocrinologica, vol. 103, no. 3, pp. 365-370.
Ferriss JB, Brown JJ, Cumming AMM, Fraser R, Lever AF, Peacock M et al. Primary hyperparathyroidism associated with primary hyperaldosteronism. Acta Endocrinologica. 1983;103(3):365-370.
Ferriss, J. B. ; Brown, J. J. ; Cumming, A. M M ; Fraser, R. ; Lever, A. F. ; Peacock, Munro ; Robertson, J. I. / Primary hyperparathyroidism associated with primary hyperaldosteronism. In: Acta Endocrinologica. 1983 ; Vol. 103, No. 3. pp. 365-370.
@article{fcc817d5b9e540b79c3bfb6fce0b28a8,
title = "Primary hyperparathyroidism associated with primary hyperaldosteronism",
abstract = "Two patients with both primary hyperparathyroidism and primary hyperaldosteronism are described. Each presented with high blood pressure and a history of renal calculi. Mild hypercalcaemia was associated with raised plasma parathyroid hormone concentrations and a parathyroid adenoma was excised from each. Both patients also had hypokalaemia, hyperaldosteronism and low plasma renin concentrations. Quadric analysis, adrenal vein plasma aldosterone concentrations, adrenal venography and CT scanning all suggested an adrenal adenoma in each patient; the other patient is unfit for adrenal surgery but her blood pressure and plasma potassium concentration have remained within the normal range during prolonged treatment with either spironolactone or amiloride. Because of this unusual association a search was made for parathyroid hormone excess in patients with primary hyperaldosteronism and for aldosterone excess in primary hyperparathyroidism. None was found.",
author = "Ferriss, {J. B.} and Brown, {J. J.} and Cumming, {A. M M} and R. Fraser and Lever, {A. F.} and Munro Peacock and Robertson, {J. I.}",
year = "1983",
language = "English (US)",
volume = "103",
pages = "365--370",
journal = "European Journal of Endocrinology",
issn = "0804-4643",
publisher = "BioScientifica Ltd.",
number = "3",

}

TY - JOUR

T1 - Primary hyperparathyroidism associated with primary hyperaldosteronism

AU - Ferriss, J. B.

AU - Brown, J. J.

AU - Cumming, A. M M

AU - Fraser, R.

AU - Lever, A. F.

AU - Peacock, Munro

AU - Robertson, J. I.

PY - 1983

Y1 - 1983

N2 - Two patients with both primary hyperparathyroidism and primary hyperaldosteronism are described. Each presented with high blood pressure and a history of renal calculi. Mild hypercalcaemia was associated with raised plasma parathyroid hormone concentrations and a parathyroid adenoma was excised from each. Both patients also had hypokalaemia, hyperaldosteronism and low plasma renin concentrations. Quadric analysis, adrenal vein plasma aldosterone concentrations, adrenal venography and CT scanning all suggested an adrenal adenoma in each patient; the other patient is unfit for adrenal surgery but her blood pressure and plasma potassium concentration have remained within the normal range during prolonged treatment with either spironolactone or amiloride. Because of this unusual association a search was made for parathyroid hormone excess in patients with primary hyperaldosteronism and for aldosterone excess in primary hyperparathyroidism. None was found.

AB - Two patients with both primary hyperparathyroidism and primary hyperaldosteronism are described. Each presented with high blood pressure and a history of renal calculi. Mild hypercalcaemia was associated with raised plasma parathyroid hormone concentrations and a parathyroid adenoma was excised from each. Both patients also had hypokalaemia, hyperaldosteronism and low plasma renin concentrations. Quadric analysis, adrenal vein plasma aldosterone concentrations, adrenal venography and CT scanning all suggested an adrenal adenoma in each patient; the other patient is unfit for adrenal surgery but her blood pressure and plasma potassium concentration have remained within the normal range during prolonged treatment with either spironolactone or amiloride. Because of this unusual association a search was made for parathyroid hormone excess in patients with primary hyperaldosteronism and for aldosterone excess in primary hyperparathyroidism. None was found.

UR - http://www.scopus.com/inward/record.url?scp=0020624394&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020624394&partnerID=8YFLogxK

M3 - Article

C2 - 6349207

AN - SCOPUS:0020624394

VL - 103

SP - 365

EP - 370

JO - European Journal of Endocrinology

JF - European Journal of Endocrinology

SN - 0804-4643

IS - 3

ER -