Primary rhabdomyosarcoma of the kidney: A light microscopic, immunohistochemical, and electron microscopic study

David J. Grignon, Gary P. McIsaac, Ross F. Armstrong, John K. Wyatt

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

Primary rhabdomyosarcoma of the kidney is a rare and highly aggressive tumor in the adult population. A case is reported in a 70‐year‐old woman with the diagnosis confirmed by immunohistochemistry and electron microscopy. This is the first case studied using the immunoperoxidase technique and the second with electron microscopic examination. To make a diagnosis of primary sarcoma, of the kidney, three criteria must be met: (1) a metastatic sarcoma must be ruled out; (2) the tumor must arise from renal parenchyma; and (3) a sarcomatoid variant of renal cell carcinoma needs to be excluded. The literature is reviewed and available clinical and pathologic details are summarized.

Original languageEnglish (US)
Pages (from-to)2027-2032
Number of pages6
JournalCancer
Volume62
Issue number9
DOIs
StatePublished - Nov 1 1988

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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