In addressing probability and the principles of diagnostic certainty associated with medical imaging, we have in essence described the science of clinical decision making, of which medical imaging is only one component. In recent years this has come under the rubric of evidence-based clinical practice. Evidence-based clinical practice is an approach to healthcare practice that explicitly acknowledges the evidence that bears on each patient management decision, the strength of that evidence, the benefits and risk of alternative management strategies, and the role of patients' values and preferences in trading off those benefits and risks. For the clinician, the best sources of evidence will be found in the published literature under such titles as systematic reviews, meta analysis, and practice and procedure guidelines published and promulgated by professional medical organizations.
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