Proliferation index is related to patient age in glioblastoma

Paul E. McKeever, L. Junck, M. S. Strawderman, M. Blaivas, A. Tkaczyk, M. A. Cates, M. Yan, L. Li

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

Younger patients with glioblastomas have a significantly better prognosis than do older patients. To determine whether patient age might be related to proliferation of glioblastoma cells, glioblastomas from patients of different ages were stained with the Molecular Immunology Borstel number 1 antibody to detect proliferating cells. Younger patient age was a significant predictor of a low Molecular Immunology Borstel number 1 proliferation index (p = 0.0001). This previously unreported association favors an intrinsic difference in the type of glioblastomas that afflict younger patients.

Original languageEnglish (US)
Pages (from-to)1216-1218
Number of pages3
JournalNeurology
Volume56
Issue number9
DOIs
StatePublished - May 8 2001

ASJC Scopus subject areas

  • Clinical Neurology

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    McKeever, P. E., Junck, L., Strawderman, M. S., Blaivas, M., Tkaczyk, A., Cates, M. A., Yan, M., & Li, L. (2001). Proliferation index is related to patient age in glioblastoma. Neurology, 56(9), 1216-1218. https://doi.org/10.1212/WNL.56.9.1216