Prospective assessment of the performance of a new fine needle biopsy device for EUS-guided sampling of solid lesions

Ihab I. El Hajj, Howard Wu, Sarah Reuss, Melissa Randolph, Akeem Harris, Mark A. Gromski, Mohammad Al-Haddad

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background/Aims: Endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) remains the most common EUS-guided tissue acquisition technique. This study aimed to evaluate the performance of a new Franseen tip fine needle biopsy (FNB) device for EUS-guided sampling of solid lesions and compare it with the historical FNA technique. Methods: Acquire® 22 G FNB needle (Boston Scientific Co., Natick, MA, USA) was used for solid tumor sampling (Study group). Tissue was collected for rapid on-site evaluation, and touch and crush preparations were made. Historical EUS-FNA samples obtained using Expect® 22 G FNA needle (Boston Scientific Co.) were used as controls (Control group). All specimens were independently evaluated by two cytopathologists blinded to the formal cytopathological diagnosis. Results: Mean cell block histology scores were significantly higher (p=0.046) in the FNB group (51 samples) despite a significantly lower (p<0.001) mean number of passes compared to the FNA group (50 specimens). The overall diagnostic yields for the FNB vs. FNA groups were 96% vs. 88%. The degree of tumor differentiation was adequately assessed in all cell block qualifying lesions in the FNB group. Two patients developed post-FNB abdominal pain. Conclusions: The new Franseen tip FNB device provides histologically superior and cytologically comparable specimens to those obtained by FNA, but with fewer passes.

Original languageEnglish (US)
Pages (from-to)576-583
Number of pages8
JournalClinical Endoscopy
Volume51
Issue number6
DOIs
StatePublished - Nov 1 2018

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Fine Needle Biopsy
Equipment and Supplies
Endoscopic Ultrasound-Guided Fine Needle Aspiration
Needles
Sampling Studies
Touch
Abdominal Pain
Neoplasms
Histology
Control Groups

Keywords

  • Endoscopic ultrasound-guided fine needle aspiration
  • Endoscopic ultrasound-guided fine needle biopsy
  • Tissue acquisition

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

Cite this

Prospective assessment of the performance of a new fine needle biopsy device for EUS-guided sampling of solid lesions. / El Hajj, Ihab I.; Wu, Howard; Reuss, Sarah; Randolph, Melissa; Harris, Akeem; Gromski, Mark A.; Al-Haddad, Mohammad.

In: Clinical Endoscopy, Vol. 51, No. 6, 01.11.2018, p. 576-583.

Research output: Contribution to journalArticle

El Hajj, Ihab I. ; Wu, Howard ; Reuss, Sarah ; Randolph, Melissa ; Harris, Akeem ; Gromski, Mark A. ; Al-Haddad, Mohammad. / Prospective assessment of the performance of a new fine needle biopsy device for EUS-guided sampling of solid lesions. In: Clinical Endoscopy. 2018 ; Vol. 51, No. 6. pp. 576-583.
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