Prospective cross-sectional study of the prevalence of incidental pancreatic cysts during routine outpatient endoscopic ultrasound

Michael Sai Lai Sey, Sean Teagarden, Diane Settles, Kathleen McGreevy, Gregory A. Coté, Stuart Sherman, Lee McHenry, Julia K. LeBlanc, Mohammad Al-Haddad, John DeWitt

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Objective: Incidental pancreatic cysts are often detected during abdominal imaging and require follow-up since some have malignant potential. Endoscopic ultrasound (EUS) is highly sensitive for pancreatic diseases, yet the prevalence of incidental pancreatic cysts discoveredwith EUS is unknown. The objective of the study was to determine its prevalence by EUS. Methods: A prospective cross-sectional study was conducted. Patients undergoing EUS for nonpancreatic indications and without known pancreatic abnormality were recruited to assess the prevalence of pancreatic cysts and its characteristics. Risk factors were determined by logistic regression. Results: We enrolled 341 patients (mean age, 59 years; 187 females) and found 46 incidental pancreatic cysts (median [range], 5 [2-80] mm) in 32 patients (9.4%). Branch duct intraductal papillary mucinous neoplasm was the most common finding. Seven cysts were larger than 1 cm and 1 adenocarcinoma was discovered. Multivariate logistic regression showed an association between pancreatic cysts and older age (odds ratio, 1.04 per year; 95% confidence interval, 1.01-1.08) and female sex (odds ratio, 3.08; 95% confidence interval, 1.25-7.45). Conclusions: In our population, the prevalence of incidental pancreatic cyst discovered on EUS was 9.4% and the majority were less than 1 cm. Increasing age and female sex were associated with the development of pancreatic cysts.

Original languageEnglish
Pages (from-to)1130-1133
Number of pages4
JournalPancreas
Volume44
Issue number7
StatePublished - Oct 1 2015

Fingerprint

Pancreatic Cyst
Outpatients
Cross-Sectional Studies
Logistic Models
Odds Ratio
Confidence Intervals
Pancreatic Diseases
Sex Ratio
Cysts
Adenocarcinoma

Keywords

  • cyst
  • endoscopic ultrasound
  • Pancreas
  • prevalence
  • risk factor

ASJC Scopus subject areas

  • Hepatology
  • Internal Medicine
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism

Cite this

Prospective cross-sectional study of the prevalence of incidental pancreatic cysts during routine outpatient endoscopic ultrasound. / Sey, Michael Sai Lai; Teagarden, Sean; Settles, Diane; McGreevy, Kathleen; Coté, Gregory A.; Sherman, Stuart; McHenry, Lee; LeBlanc, Julia K.; Al-Haddad, Mohammad; DeWitt, John.

In: Pancreas, Vol. 44, No. 7, 01.10.2015, p. 1130-1133.

Research output: Contribution to journalArticle

Sey, MSL, Teagarden, S, Settles, D, McGreevy, K, Coté, GA, Sherman, S, McHenry, L, LeBlanc, JK, Al-Haddad, M & DeWitt, J 2015, 'Prospective cross-sectional study of the prevalence of incidental pancreatic cysts during routine outpatient endoscopic ultrasound', Pancreas, vol. 44, no. 7, pp. 1130-1133.
Sey, Michael Sai Lai ; Teagarden, Sean ; Settles, Diane ; McGreevy, Kathleen ; Coté, Gregory A. ; Sherman, Stuart ; McHenry, Lee ; LeBlanc, Julia K. ; Al-Haddad, Mohammad ; DeWitt, John. / Prospective cross-sectional study of the prevalence of incidental pancreatic cysts during routine outpatient endoscopic ultrasound. In: Pancreas. 2015 ; Vol. 44, No. 7. pp. 1130-1133.
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AU - Sherman, Stuart

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AB - Objective: Incidental pancreatic cysts are often detected during abdominal imaging and require follow-up since some have malignant potential. Endoscopic ultrasound (EUS) is highly sensitive for pancreatic diseases, yet the prevalence of incidental pancreatic cysts discoveredwith EUS is unknown. The objective of the study was to determine its prevalence by EUS. Methods: A prospective cross-sectional study was conducted. Patients undergoing EUS for nonpancreatic indications and without known pancreatic abnormality were recruited to assess the prevalence of pancreatic cysts and its characteristics. Risk factors were determined by logistic regression. Results: We enrolled 341 patients (mean age, 59 years; 187 females) and found 46 incidental pancreatic cysts (median [range], 5 [2-80] mm) in 32 patients (9.4%). Branch duct intraductal papillary mucinous neoplasm was the most common finding. Seven cysts were larger than 1 cm and 1 adenocarcinoma was discovered. Multivariate logistic regression showed an association between pancreatic cysts and older age (odds ratio, 1.04 per year; 95% confidence interval, 1.01-1.08) and female sex (odds ratio, 3.08; 95% confidence interval, 1.25-7.45). Conclusions: In our population, the prevalence of incidental pancreatic cyst discovered on EUS was 9.4% and the majority were less than 1 cm. Increasing age and female sex were associated with the development of pancreatic cysts.

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