Prostate changes related to therapy: With special reference to hormone therapy

Roberta Mazzucchelli, Antonio Lopez-Beltran, Andrea B. Galosi, Antonio Zizzi, Marina Scarpelli, Sergio Bracarda, Liang Cheng, Rodolfo Montironi

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

Hormone and radiation therapy have traditionally been used in prostate cancer (PCa). Morphological effects are often identified in needle biopsies and surgical specimens. A range of histological changes are seen in the non-neoplastic prostate and in the pre-neoplastic and neoplastic areas. Other ablative therapies, including cryotherapy, and emerging focal therapies, such as high-intensity focused ultrasound, photodynamic therapy and interstitial laser thermotherapy, may induce changes on the prostate. As new compounds are developed for prostate cancer treatment, it is important to document their effects on benign and neoplastic prostate tissue.

Original languageEnglish (US)
Pages (from-to)1873-1886
Number of pages14
JournalFuture Oncology
Volume10
Issue number11
DOIs
StatePublished - Sep 1 2014

Keywords

  • Cryotherapy
  • Emerging ablative therapies
  • Hormone therapy
  • Nutritional supplements
  • Prostate cancer
  • Radiation therapy
  • Target molecular therapies

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Medicine(all)

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  • Cite this

    Mazzucchelli, R., Lopez-Beltran, A., Galosi, A. B., Zizzi, A., Scarpelli, M., Bracarda, S., Cheng, L., & Montironi, R. (2014). Prostate changes related to therapy: With special reference to hormone therapy. Future Oncology, 10(11), 1873-1886. https://doi.org/10.2217/FON.14.37