Prosthetic replacement for the thoracic vena cava. An experimental study

A. C. Fiore, John Brown, R. S. Cromartie, L. C. Ofstein, P. S. Peigh, N. S. Sears, W. P. Deschner, H. King

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

The superior vena cava (SVC) and thoracic inferior vena cava (IVC) were replaced in 46 dogs with autologous vein, knitted Dacron, glutaraldehyde-fixed porcine pericardium, unsupported polytetrafluoroethylene (PTFE), and externally stented PTFE. After 30 days, patency rates were determined by contrast venography and were 100%, 0%, 50%, 75%, and 100%, respectively. The patency rates of Dacron and glutaraldehyde-fixed pericardium are considered unacceptable when compared to autologous vein (p < 0.05). Stented PTFE exhibited a patency rate equal to that of autologous vein at 30 days, minimal graft reaction, excellent incorporation by host fibroblasts, and a smooth neointima. The external spiral support added to PTFE enhanced the thromboresistance of this graft in the thoracic venous system. Long-term follow-up is required to determine if the stented PTFE prosthesis remains comparable to autologous vein as a venous conduit.

Original languageEnglish
Pages (from-to)560-568
Number of pages9
JournalJournal of Thoracic and Cardiovascular Surgery
Volume84
Issue number4
StatePublished - 1982

Fingerprint

Venae Cavae
Polytetrafluoroethylene
Thorax
Veins
Polyethylene Terephthalates
Pericardium
Glutaral
Transplants
Neointima
Superior Vena Cava
Phlebography
Inferior Vena Cava
Prostheses and Implants
Swine
Fibroblasts
Dogs

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery

Cite this

Fiore, A. C., Brown, J., Cromartie, R. S., Ofstein, L. C., Peigh, P. S., Sears, N. S., ... King, H. (1982). Prosthetic replacement for the thoracic vena cava. An experimental study. Journal of Thoracic and Cardiovascular Surgery, 84(4), 560-568.

Prosthetic replacement for the thoracic vena cava. An experimental study. / Fiore, A. C.; Brown, John; Cromartie, R. S.; Ofstein, L. C.; Peigh, P. S.; Sears, N. S.; Deschner, W. P.; King, H.

In: Journal of Thoracic and Cardiovascular Surgery, Vol. 84, No. 4, 1982, p. 560-568.

Research output: Contribution to journalArticle

Fiore, AC, Brown, J, Cromartie, RS, Ofstein, LC, Peigh, PS, Sears, NS, Deschner, WP & King, H 1982, 'Prosthetic replacement for the thoracic vena cava. An experimental study', Journal of Thoracic and Cardiovascular Surgery, vol. 84, no. 4, pp. 560-568.
Fiore AC, Brown J, Cromartie RS, Ofstein LC, Peigh PS, Sears NS et al. Prosthetic replacement for the thoracic vena cava. An experimental study. Journal of Thoracic and Cardiovascular Surgery. 1982;84(4):560-568.
Fiore, A. C. ; Brown, John ; Cromartie, R. S. ; Ofstein, L. C. ; Peigh, P. S. ; Sears, N. S. ; Deschner, W. P. ; King, H. / Prosthetic replacement for the thoracic vena cava. An experimental study. In: Journal of Thoracic and Cardiovascular Surgery. 1982 ; Vol. 84, No. 4. pp. 560-568.
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