Psychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report)

Epilepsy and autism

Frank Besag, Albert Aldenkamp, Rochelle Caplan, David Dunn, Giuseppe Gobbi, Matti Sillanpää

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A high proportion of children with epilepsy have autism spectrum disorder. Although estimates vary, depending both on the population studied and the definitions used, a figure of around 20% has typically been reported. Autism can have a major impact on the life of the child and family. Despite the importance of this comorbidity and although many studies have been performed, a full understanding of the possible links between epilepsy and autism remains elusive. In a minority of cases, for example in the Landau-Kleffner syndrome, the autistic features can be the result of the epilepsy itself. However, there has been a failure to demonstrate that the epilepsy itself plays a major role in most cases. The current evidence seems to point to a common underlying predisposing factor. The discovery of a growing number of genetic defects leading to both conditions would support this explanation of the link.

Original languageEnglish (US)
Pages (from-to)S16-S23
JournalEpileptic Disorders
Volume18
StatePublished - May 1 2016

Fingerprint

Advisory Committees
Autistic Disorder
Psychiatry
Epilepsy
Landau-Kleffner Syndrome
Causality
Comorbidity
Population

Keywords

  • Autism
  • CSWS
  • Epileptiform
  • ESES
  • Landau-Kleffner

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Besag, F., Aldenkamp, A., Caplan, R., Dunn, D., Gobbi, G., & Sillanpää, M. (2016). Psychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report): Epilepsy and autism. Epileptic Disorders, 18, S16-S23.

Psychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report) : Epilepsy and autism. / Besag, Frank; Aldenkamp, Albert; Caplan, Rochelle; Dunn, David; Gobbi, Giuseppe; Sillanpää, Matti.

In: Epileptic Disorders, Vol. 18, 01.05.2016, p. S16-S23.

Research output: Contribution to journalArticle

Besag, F, Aldenkamp, A, Caplan, R, Dunn, D, Gobbi, G & Sillanpää, M 2016, 'Psychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report): Epilepsy and autism', Epileptic Disorders, vol. 18, pp. S16-S23.
Besag, Frank ; Aldenkamp, Albert ; Caplan, Rochelle ; Dunn, David ; Gobbi, Giuseppe ; Sillanpää, Matti. / Psychiatric and behavioural disorders in children with epilepsy (ILAE Task Force Report) : Epilepsy and autism. In: Epileptic Disorders. 2016 ; Vol. 18. pp. S16-S23.
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