Pulmonary histoplasmosis

Jud W. Gurney, Dewey Conces

Research output: Contribution to journalReview article

70 Citations (Scopus)

Abstract

Histoplasmosis is a common infection in the central United States and is acquired through inhalation of airborne spores. The majority of infected persons have an asymptomatic, self-limiting illness. Clinical pneumonia occurs in those with exposure to a large number of infecting spores. Resolution of the pneumonia often leaves calcified pulmonary nodules, calcified mediastinal lymph nodes, or splenic calcifications. Chronic disease, which mimics tuberculosis, may develop in those with underlying emphysema. In patients with deficient cell-mediated immunity, Histoplasma capsulatum may disseminate throughout the body; this often is fatal. Delayed manifestations arise months or years after the primary infection, Broncholithiasis occurs when peribronchial calcific nodes produce bronchial obstruction. Mediastinal granuloma is the continued proliferation of fibrous tissue in draining mediastinal lymph nodes. These granulomas may obstruct adjacent veins, arteries, or airways and lead to various clinical symptoms.

Original languageEnglish (US)
Pages (from-to)297-306
Number of pages10
JournalRadiology
Volume199
Issue number2
StatePublished - May 1996

Fingerprint

Histoplasmosis
Granuloma
Spores
Pneumonia
Lymph Nodes
Histoplasma
Lung
Emphysema
Infection
Cellular Immunity
Inhalation
Veins
Tuberculosis
Chronic Disease
Arteries

Keywords

  • Bronchi, obstruction
  • Histoplasmosis
  • Lung, granuloma
  • Mediastinum, fibrosis
  • State-of-art reviews

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Gurney, J. W., & Conces, D. (1996). Pulmonary histoplasmosis. Radiology, 199(2), 297-306.

Pulmonary histoplasmosis. / Gurney, Jud W.; Conces, Dewey.

In: Radiology, Vol. 199, No. 2, 05.1996, p. 297-306.

Research output: Contribution to journalReview article

Gurney, JW & Conces, D 1996, 'Pulmonary histoplasmosis', Radiology, vol. 199, no. 2, pp. 297-306.
Gurney JW, Conces D. Pulmonary histoplasmosis. Radiology. 1996 May;199(2):297-306.
Gurney, Jud W. ; Conces, Dewey. / Pulmonary histoplasmosis. In: Radiology. 1996 ; Vol. 199, No. 2. pp. 297-306.
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