Pulmonary veins and ligament of Marshall as sources of rapid activations in a canine model of sustained atrial fibrillation

Tsu Juey Wu, James J C Ong, Che Ming Chang, Rahul N. Doshi, Masaaki Yashima, Hsun Lun A Huang, Michael C. Fishbein, Chih Tai Ting, Hrayr S. Karagueuzian, Peng-Sheng Chen

Research output: Contribution to journalArticle

163 Citations (Scopus)

Abstract

Background - In dogs, chronic rapid pacing may result in sustained atrial fibrillation (AF). However, activation patterns in pacing-induced sustained AF are unclear. Methods and Results - We induced sustained AF (>48 hours) in 6 dogs by rapid pacing for 139±84 days. We then performed computerized atrial epicardial mappings and recorded the activations in the ligament of Marshall (LOM) and the pulmonary veins (PVs). During AF, mean activation cycle length in the right atrial tree wall (126±17 ms) was significantly longer than that in the left atrial free wall (96±5 ms, P=0.006). In addition, mean activation cycle length in the left atrial free wall was significantly longer than that in the LOM (84±5 ms, P

Original languageEnglish (US)
Pages (from-to)1157-1163
Number of pages7
JournalCirculation
Volume103
Issue number8
StatePublished - Feb 27 2001
Externally publishedYes

Fingerprint

Pulmonary Veins
Ligaments
Atrial Fibrillation
Canidae
Epicardial Mapping
Dogs
carbosulfan

Keywords

  • Arrhythmia
  • Fibrillation
  • Mapping
  • Pacing
  • Pathology

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine

Cite this

Wu, T. J., Ong, J. J. C., Chang, C. M., Doshi, R. N., Yashima, M., Huang, H. L. A., ... Chen, P-S. (2001). Pulmonary veins and ligament of Marshall as sources of rapid activations in a canine model of sustained atrial fibrillation. Circulation, 103(8), 1157-1163.

Pulmonary veins and ligament of Marshall as sources of rapid activations in a canine model of sustained atrial fibrillation. / Wu, Tsu Juey; Ong, James J C; Chang, Che Ming; Doshi, Rahul N.; Yashima, Masaaki; Huang, Hsun Lun A; Fishbein, Michael C.; Ting, Chih Tai; Karagueuzian, Hrayr S.; Chen, Peng-Sheng.

In: Circulation, Vol. 103, No. 8, 27.02.2001, p. 1157-1163.

Research output: Contribution to journalArticle

Wu, TJ, Ong, JJC, Chang, CM, Doshi, RN, Yashima, M, Huang, HLA, Fishbein, MC, Ting, CT, Karagueuzian, HS & Chen, P-S 2001, 'Pulmonary veins and ligament of Marshall as sources of rapid activations in a canine model of sustained atrial fibrillation', Circulation, vol. 103, no. 8, pp. 1157-1163.
Wu TJ, Ong JJC, Chang CM, Doshi RN, Yashima M, Huang HLA et al. Pulmonary veins and ligament of Marshall as sources of rapid activations in a canine model of sustained atrial fibrillation. Circulation. 2001 Feb 27;103(8):1157-1163.
Wu, Tsu Juey ; Ong, James J C ; Chang, Che Ming ; Doshi, Rahul N. ; Yashima, Masaaki ; Huang, Hsun Lun A ; Fishbein, Michael C. ; Ting, Chih Tai ; Karagueuzian, Hrayr S. ; Chen, Peng-Sheng. / Pulmonary veins and ligament of Marshall as sources of rapid activations in a canine model of sustained atrial fibrillation. In: Circulation. 2001 ; Vol. 103, No. 8. pp. 1157-1163.
@article{142061a0de9645acb5a84d75cca7efd5,
title = "Pulmonary veins and ligament of Marshall as sources of rapid activations in a canine model of sustained atrial fibrillation",
abstract = "Background - In dogs, chronic rapid pacing may result in sustained atrial fibrillation (AF). However, activation patterns in pacing-induced sustained AF are unclear. Methods and Results - We induced sustained AF (>48 hours) in 6 dogs by rapid pacing for 139±84 days. We then performed computerized atrial epicardial mappings and recorded the activations in the ligament of Marshall (LOM) and the pulmonary veins (PVs). During AF, mean activation cycle length in the right atrial tree wall (126±17 ms) was significantly longer than that in the left atrial free wall (96±5 ms, P=0.006). In addition, mean activation cycle length in the left atrial free wall was significantly longer than that in the LOM (84±5 ms, P",
keywords = "Arrhythmia, Fibrillation, Mapping, Pacing, Pathology",
author = "Wu, {Tsu Juey} and Ong, {James J C} and Chang, {Che Ming} and Doshi, {Rahul N.} and Masaaki Yashima and Huang, {Hsun Lun A} and Fishbein, {Michael C.} and Ting, {Chih Tai} and Karagueuzian, {Hrayr S.} and Peng-Sheng Chen",
year = "2001",
month = "2",
day = "27",
language = "English (US)",
volume = "103",
pages = "1157--1163",
journal = "Circulation",
issn = "0009-7322",
publisher = "Lippincott Williams and Wilkins",
number = "8",

}

TY - JOUR

T1 - Pulmonary veins and ligament of Marshall as sources of rapid activations in a canine model of sustained atrial fibrillation

AU - Wu, Tsu Juey

AU - Ong, James J C

AU - Chang, Che Ming

AU - Doshi, Rahul N.

AU - Yashima, Masaaki

AU - Huang, Hsun Lun A

AU - Fishbein, Michael C.

AU - Ting, Chih Tai

AU - Karagueuzian, Hrayr S.

AU - Chen, Peng-Sheng

PY - 2001/2/27

Y1 - 2001/2/27

N2 - Background - In dogs, chronic rapid pacing may result in sustained atrial fibrillation (AF). However, activation patterns in pacing-induced sustained AF are unclear. Methods and Results - We induced sustained AF (>48 hours) in 6 dogs by rapid pacing for 139±84 days. We then performed computerized atrial epicardial mappings and recorded the activations in the ligament of Marshall (LOM) and the pulmonary veins (PVs). During AF, mean activation cycle length in the right atrial tree wall (126±17 ms) was significantly longer than that in the left atrial free wall (96±5 ms, P=0.006). In addition, mean activation cycle length in the left atrial free wall was significantly longer than that in the LOM (84±5 ms, P

AB - Background - In dogs, chronic rapid pacing may result in sustained atrial fibrillation (AF). However, activation patterns in pacing-induced sustained AF are unclear. Methods and Results - We induced sustained AF (>48 hours) in 6 dogs by rapid pacing for 139±84 days. We then performed computerized atrial epicardial mappings and recorded the activations in the ligament of Marshall (LOM) and the pulmonary veins (PVs). During AF, mean activation cycle length in the right atrial tree wall (126±17 ms) was significantly longer than that in the left atrial free wall (96±5 ms, P=0.006). In addition, mean activation cycle length in the left atrial free wall was significantly longer than that in the LOM (84±5 ms, P

KW - Arrhythmia

KW - Fibrillation

KW - Mapping

KW - Pacing

KW - Pathology

UR - http://www.scopus.com/inward/record.url?scp=0035957046&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035957046&partnerID=8YFLogxK

M3 - Article

C2 - 11222481

AN - SCOPUS:0035957046

VL - 103

SP - 1157

EP - 1163

JO - Circulation

JF - Circulation

SN - 0009-7322

IS - 8

ER -