Pulsed laser radiation effects on the distribution of conduction velocities in sciatic nerve of the rat

Shien-Fong Lin, Ursula Wesselmann, William Z. Rymer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The effects of subablative Q-switched Nd-YAG laser irradiation on the nerve fiber population of the sciatic nerve in rat were estimated using a quantitative method. The acute and cumulative effects were evaluated separately. When 5-minute laser irradiation was applied to the sciatic nerve, there was a differential decrease in the number of active fibers in slow and fast fiber classes. Fast fibers were insensitive to the radiation as the number of fibers was not altered significantly except at high radiating energies. The amount of decrease in each fiber class was not strictly proportional to the radiating laser energy. The cumulative effects show an exponential decay in fiber number after radiation sequence of gradually incremented laser pulse energy. Similarly, the impairment of fast fiber classes was less significant than slow fiber classes. At high cumulative optical energy, the number of fibers in fast fiber classes started decreasing whereas fiber population in slow fiber classes increased. We postulate that the impairment of the node of Ranvier was the dominant mechanism at low energy radiation, whereas the change in the cable properties of internodes resulted in the shift of fast fibers to slower fiber classes.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsStephen N. Joffe, Kazuhiko Atsumi
PublisherPubl by Int Soc for Optical Engineering
Pages334-342
Number of pages9
Volume1200
ISBN (Print)0819402419
StatePublished - 1990
Externally publishedYes
EventProceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II - Los Angeles, CA, USA
Duration: Jan 14 1990Jan 19 1990

Other

OtherProceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II
CityLos Angeles, CA, USA
Period1/14/901/19/90

Fingerprint

Radiation effects
nerves
radiation effects
Laser radiation
Pulsed lasers
rats
Rats
pulsed lasers
laser beams
conduction
fibers
Fibers
impairment
Laser beam effects
Radiation
radiation
energy
lasers
nerve fibers
irradiation

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Lin, S-F., Wesselmann, U., & Rymer, W. Z. (1990). Pulsed laser radiation effects on the distribution of conduction velocities in sciatic nerve of the rat. In S. N. Joffe, & K. Atsumi (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 1200, pp. 334-342). Publ by Int Soc for Optical Engineering.

Pulsed laser radiation effects on the distribution of conduction velocities in sciatic nerve of the rat. / Lin, Shien-Fong; Wesselmann, Ursula; Rymer, William Z.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / Stephen N. Joffe; Kazuhiko Atsumi. Vol. 1200 Publ by Int Soc for Optical Engineering, 1990. p. 334-342.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Lin, S-F, Wesselmann, U & Rymer, WZ 1990, Pulsed laser radiation effects on the distribution of conduction velocities in sciatic nerve of the rat. in SN Joffe & K Atsumi (eds), Proceedings of SPIE - The International Society for Optical Engineering. vol. 1200, Publ by Int Soc for Optical Engineering, pp. 334-342, Proceedings of Laser Surgery: Advanced Characterization Therapeutics, and Systems II, Los Angeles, CA, USA, 1/14/90.
Lin S-F, Wesselmann U, Rymer WZ. Pulsed laser radiation effects on the distribution of conduction velocities in sciatic nerve of the rat. In Joffe SN, Atsumi K, editors, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 1200. Publ by Int Soc for Optical Engineering. 1990. p. 334-342
Lin, Shien-Fong ; Wesselmann, Ursula ; Rymer, William Z. / Pulsed laser radiation effects on the distribution of conduction velocities in sciatic nerve of the rat. Proceedings of SPIE - The International Society for Optical Engineering. editor / Stephen N. Joffe ; Kazuhiko Atsumi. Vol. 1200 Publ by Int Soc for Optical Engineering, 1990. pp. 334-342
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