Quality of life immediately after peripheral blood stem cell transplantation

Eileen Danaher Hacker, Carol Estwing Ferrans

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


This prospective, longitudinal study investigated the quality of life among patients immediately after undergoing peripheral blood stem cell transplantation. The patients were assessed before transplantation (n = 16), immediately before hospital discharge (n = 10), 2 weeks after hospital discharge (n = 10), and 6 weeks after hospital discharge (n = 8). Patients completed the European Organization for Research and Training Quality of Life Questionnaire-Core 30 and the Ferrans and Powers Quality of Life Index at each assessment point. A brief telephone interview was conducted 6 weeks after hospitalization (n = 7). The study results indicate that patients undergoing peripheral blood stem cell transplantation experience significant appetite loss (P < .01), diarrhea (P < .05), nausea and vomiting (P < .05), and sleep disturbances (P < .01) during the acute posttransplantation period. Other clinically important changes also were identified, so that a general pattern of recovery emerged. These patients reported diminished functional ability, increased symptoms, and poorer quality of life immediately before hospital discharge, with a return to pretransplantation levels by 6 weeks after hospitalization. In contrast, life satisfaction continued to decline 2 weeks after hospitalization, but did improve by 6 weeks. The qualitative data provide further support for this trend.

Original languageEnglish (US)
Pages (from-to)312-322
Number of pages11
JournalCancer nursing
Issue number4
StatePublished - Aug 2003
Externally publishedYes


  • Functional status
  • Life satisfaction
  • Quality of life
  • Stem cell transplantation

ASJC Scopus subject areas

  • Oncology
  • Oncology(nursing)

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