Abstract
Objective The primary aim of this study was to determine if there is a change in the quality of life in pediatric patients with unremitting functional constipation and/or encopresis after undergoing a MACE procedure. Methods Patients, ages 5 to 18 years with unremitting constipation and a normal evaluation, including anorectal manometry and colonic manometry, who opted to undergo a MACE procedure were contacted to participate in the study. Patients with congenital anorectal malformations as well as spinal cord disorders were excluded from the study. The patient's parent/guardian completed the PedsQL™ Generic Core Scales QOL survey prior to the operation, 6 months, and 12 months after the procedure. Results A total of 15 consecutive patients meeting protocol criteria were recruited within a period of 20 months. The mean age at the MACE procedure was 9.8 years (range 7.0-11.1). 5 patients were female. The mean QOL score pre-MACE was 64.1. At 6 months post-MACE the mean overall QOL score was 90.2, and it was 92.0 at 12 months. All 15 patients at the 6 month follow up had significant improvement in their QOL (p = 1.9 × 10- 7) and all subcategories of QOL were significantly improved as well. Conclusions A MACE procedure is of benefit to otherwise normal pediatric patients who have unremitting functional constipation with failure of medical treatment. Our patients had a significant improvement in all QOL categories and overall QOL.
| Original language | English |
|---|---|
| Pages (from-to) | 1733-1737 |
| Number of pages | 5 |
| Journal | Journal of Pediatric Surgery |
| Volume | 48 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 2013 |
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Keywords
- Functional constipation
- Malone antegrade continence enema
- Quality of life
ASJC Scopus subject areas
- Surgery
- Pediatrics, Perinatology, and Child Health
Cite this
Quality of life in pediatric patients with unremitting constipation pre and post Malone Antegrade Continence Enema (MACE) procedure. / Har, Aileen F.; Rescorla, Frederick; Croffie, Joseph.
In: Journal of Pediatric Surgery, Vol. 48, No. 8, 08.2013, p. 1733-1737.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Quality of life in pediatric patients with unremitting constipation pre and post Malone Antegrade Continence Enema (MACE) procedure
AU - Har, Aileen F.
AU - Rescorla, Frederick
AU - Croffie, Joseph
PY - 2013/8
Y1 - 2013/8
N2 - Objective The primary aim of this study was to determine if there is a change in the quality of life in pediatric patients with unremitting functional constipation and/or encopresis after undergoing a MACE procedure. Methods Patients, ages 5 to 18 years with unremitting constipation and a normal evaluation, including anorectal manometry and colonic manometry, who opted to undergo a MACE procedure were contacted to participate in the study. Patients with congenital anorectal malformations as well as spinal cord disorders were excluded from the study. The patient's parent/guardian completed the PedsQL™ Generic Core Scales QOL survey prior to the operation, 6 months, and 12 months after the procedure. Results A total of 15 consecutive patients meeting protocol criteria were recruited within a period of 20 months. The mean age at the MACE procedure was 9.8 years (range 7.0-11.1). 5 patients were female. The mean QOL score pre-MACE was 64.1. At 6 months post-MACE the mean overall QOL score was 90.2, and it was 92.0 at 12 months. All 15 patients at the 6 month follow up had significant improvement in their QOL (p = 1.9 × 10- 7) and all subcategories of QOL were significantly improved as well. Conclusions A MACE procedure is of benefit to otherwise normal pediatric patients who have unremitting functional constipation with failure of medical treatment. Our patients had a significant improvement in all QOL categories and overall QOL.
AB - Objective The primary aim of this study was to determine if there is a change in the quality of life in pediatric patients with unremitting functional constipation and/or encopresis after undergoing a MACE procedure. Methods Patients, ages 5 to 18 years with unremitting constipation and a normal evaluation, including anorectal manometry and colonic manometry, who opted to undergo a MACE procedure were contacted to participate in the study. Patients with congenital anorectal malformations as well as spinal cord disorders were excluded from the study. The patient's parent/guardian completed the PedsQL™ Generic Core Scales QOL survey prior to the operation, 6 months, and 12 months after the procedure. Results A total of 15 consecutive patients meeting protocol criteria were recruited within a period of 20 months. The mean age at the MACE procedure was 9.8 years (range 7.0-11.1). 5 patients were female. The mean QOL score pre-MACE was 64.1. At 6 months post-MACE the mean overall QOL score was 90.2, and it was 92.0 at 12 months. All 15 patients at the 6 month follow up had significant improvement in their QOL (p = 1.9 × 10- 7) and all subcategories of QOL were significantly improved as well. Conclusions A MACE procedure is of benefit to otherwise normal pediatric patients who have unremitting functional constipation with failure of medical treatment. Our patients had a significant improvement in all QOL categories and overall QOL.
KW - Functional constipation
KW - Malone antegrade continence enema
KW - Quality of life
UR - http://www.scopus.com/inward/record.url?scp=84881412569&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84881412569&partnerID=8YFLogxK
U2 - 10.1016/j.jpedsurg.2013.01.045
DO - 10.1016/j.jpedsurg.2013.01.045
M3 - Article
C2 - 23932614
AN - SCOPUS:84881412569
VL - 48
SP - 1733
EP - 1737
JO - Journal of Pediatric Surgery
JF - Journal of Pediatric Surgery
SN - 0022-3468
IS - 8
ER -