Abstract
Objectives: To develop a method for assessing absolute renal function (as well as morphology) in children, using gamma camera imaging of intravenously injected technetium-99m (99mTc) dimercaptosuccinic acid (DMSA). Methods. Forty-five children (ages 1 week to 10 years; mean, 2.0 years) were imaged using a planar technique in which not only the appearance but the absolute amount of intravenously administered 99mTc DMSA taken up by the kidneys was calculated for each child and compared with contemporaneous determinations of creatinine clearance. Results. There was a close correlation between the absolute DMSA uptake and creatinine clearance (r = 0.752). Conclusions. Renal function in children, expressed as creatinine clearance, can be accurately estimated by measuring absolute DMSA uptake with planar gamma camera imaging using 99mTc DMSA.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 405-408 |
| Number of pages | 4 |
| Journal | Urology |
| Volume | 47 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1996 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Urology
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Quantitative technetium-99m dimercaptosuccinic acid renal scanning in children. / Goodgold, Henry M.; Fletcher, James; Steinhardt, George F.
In: Urology, Vol. 47, No. 3, 03.1996, p. 405-408.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Quantitative technetium-99m dimercaptosuccinic acid renal scanning in children
AU - Goodgold, Henry M.
AU - Fletcher, James
AU - Steinhardt, George F.
PY - 1996/3
Y1 - 1996/3
N2 - Objectives: To develop a method for assessing absolute renal function (as well as morphology) in children, using gamma camera imaging of intravenously injected technetium-99m (99mTc) dimercaptosuccinic acid (DMSA). Methods. Forty-five children (ages 1 week to 10 years; mean, 2.0 years) were imaged using a planar technique in which not only the appearance but the absolute amount of intravenously administered 99mTc DMSA taken up by the kidneys was calculated for each child and compared with contemporaneous determinations of creatinine clearance. Results. There was a close correlation between the absolute DMSA uptake and creatinine clearance (r = 0.752). Conclusions. Renal function in children, expressed as creatinine clearance, can be accurately estimated by measuring absolute DMSA uptake with planar gamma camera imaging using 99mTc DMSA.
AB - Objectives: To develop a method for assessing absolute renal function (as well as morphology) in children, using gamma camera imaging of intravenously injected technetium-99m (99mTc) dimercaptosuccinic acid (DMSA). Methods. Forty-five children (ages 1 week to 10 years; mean, 2.0 years) were imaged using a planar technique in which not only the appearance but the absolute amount of intravenously administered 99mTc DMSA taken up by the kidneys was calculated for each child and compared with contemporaneous determinations of creatinine clearance. Results. There was a close correlation between the absolute DMSA uptake and creatinine clearance (r = 0.752). Conclusions. Renal function in children, expressed as creatinine clearance, can be accurately estimated by measuring absolute DMSA uptake with planar gamma camera imaging using 99mTc DMSA.
UR - http://www.scopus.com/inward/record.url?scp=0029923288&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029923288&partnerID=8YFLogxK
U2 - 10.1016/S0090-4295(99)80461-0
DO - 10.1016/S0090-4295(99)80461-0
M3 - Article
C2 - 8633410
AN - SCOPUS:0029923288
VL - 47
SP - 405
EP - 408
JO - Urology
JF - Urology
SN - 0090-4295
IS - 3
ER -