Quantitative technetium-99m dimercaptosuccinic acid renal scanning in children

Henry M. Goodgold, James Fletcher, George F. Steinhardt

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Objectives: To develop a method for assessing absolute renal function (as well as morphology) in children, using gamma camera imaging of intravenously injected technetium-99m (99mTc) dimercaptosuccinic acid (DMSA). Methods. Forty-five children (ages 1 week to 10 years; mean, 2.0 years) were imaged using a planar technique in which not only the appearance but the absolute amount of intravenously administered 99mTc DMSA taken up by the kidneys was calculated for each child and compared with contemporaneous determinations of creatinine clearance. Results. There was a close correlation between the absolute DMSA uptake and creatinine clearance (r = 0.752). Conclusions. Renal function in children, expressed as creatinine clearance, can be accurately estimated by measuring absolute DMSA uptake with planar gamma camera imaging using 99mTc DMSA.

Original languageEnglish (US)
Pages (from-to)405-408
Number of pages4
JournalUrology
Volume47
Issue number3
DOIs
StatePublished - Mar 1996
Externally publishedYes

Fingerprint

Technetium Tc 99m Dimercaptosuccinic Acid
Succimer
Kidney
Creatinine
Radionuclide Imaging

ASJC Scopus subject areas

  • Urology

Cite this

Quantitative technetium-99m dimercaptosuccinic acid renal scanning in children. / Goodgold, Henry M.; Fletcher, James; Steinhardt, George F.

In: Urology, Vol. 47, No. 3, 03.1996, p. 405-408.

Research output: Contribution to journalArticle

Goodgold, Henry M. ; Fletcher, James ; Steinhardt, George F. / Quantitative technetium-99m dimercaptosuccinic acid renal scanning in children. In: Urology. 1996 ; Vol. 47, No. 3. pp. 405-408.
@article{9e6d7c65de8c4f9f87c696e86c5b064e,
title = "Quantitative technetium-99m dimercaptosuccinic acid renal scanning in children",
abstract = "Objectives: To develop a method for assessing absolute renal function (as well as morphology) in children, using gamma camera imaging of intravenously injected technetium-99m (99mTc) dimercaptosuccinic acid (DMSA). Methods. Forty-five children (ages 1 week to 10 years; mean, 2.0 years) were imaged using a planar technique in which not only the appearance but the absolute amount of intravenously administered 99mTc DMSA taken up by the kidneys was calculated for each child and compared with contemporaneous determinations of creatinine clearance. Results. There was a close correlation between the absolute DMSA uptake and creatinine clearance (r = 0.752). Conclusions. Renal function in children, expressed as creatinine clearance, can be accurately estimated by measuring absolute DMSA uptake with planar gamma camera imaging using 99mTc DMSA.",
author = "Goodgold, {Henry M.} and James Fletcher and Steinhardt, {George F.}",
year = "1996",
month = "3",
doi = "10.1016/S0090-4295(99)80461-0",
language = "English (US)",
volume = "47",
pages = "405--408",
journal = "Urology",
issn = "0090-4295",
publisher = "Elsevier Inc.",
number = "3",

}

TY - JOUR

T1 - Quantitative technetium-99m dimercaptosuccinic acid renal scanning in children

AU - Goodgold, Henry M.

AU - Fletcher, James

AU - Steinhardt, George F.

PY - 1996/3

Y1 - 1996/3

N2 - Objectives: To develop a method for assessing absolute renal function (as well as morphology) in children, using gamma camera imaging of intravenously injected technetium-99m (99mTc) dimercaptosuccinic acid (DMSA). Methods. Forty-five children (ages 1 week to 10 years; mean, 2.0 years) were imaged using a planar technique in which not only the appearance but the absolute amount of intravenously administered 99mTc DMSA taken up by the kidneys was calculated for each child and compared with contemporaneous determinations of creatinine clearance. Results. There was a close correlation between the absolute DMSA uptake and creatinine clearance (r = 0.752). Conclusions. Renal function in children, expressed as creatinine clearance, can be accurately estimated by measuring absolute DMSA uptake with planar gamma camera imaging using 99mTc DMSA.

AB - Objectives: To develop a method for assessing absolute renal function (as well as morphology) in children, using gamma camera imaging of intravenously injected technetium-99m (99mTc) dimercaptosuccinic acid (DMSA). Methods. Forty-five children (ages 1 week to 10 years; mean, 2.0 years) were imaged using a planar technique in which not only the appearance but the absolute amount of intravenously administered 99mTc DMSA taken up by the kidneys was calculated for each child and compared with contemporaneous determinations of creatinine clearance. Results. There was a close correlation between the absolute DMSA uptake and creatinine clearance (r = 0.752). Conclusions. Renal function in children, expressed as creatinine clearance, can be accurately estimated by measuring absolute DMSA uptake with planar gamma camera imaging using 99mTc DMSA.

UR - http://www.scopus.com/inward/record.url?scp=0029923288&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029923288&partnerID=8YFLogxK

U2 - 10.1016/S0090-4295(99)80461-0

DO - 10.1016/S0090-4295(99)80461-0

M3 - Article

VL - 47

SP - 405

EP - 408

JO - Urology

JF - Urology

SN - 0090-4295

IS - 3

ER -