QUIESCENT HERPES SIMPLEX KERATITIS REACTIVATION after INTRAVITREAL INJECTION of DEXAMETHASONE IMPLANT

Denis Jusufbegovic, Shlomit Schaal

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Purpose: To report reactivation of herpes simplex virus keratitis after the injection of dexamethasone implant (Ozurdex) and to raise the awareness of this potentially vision threatening side effect. Methods: A 90-year-old man presented with ocular pain and tearing in the left eye 3 weeks after receiving a dexamethasone implant (Ozurdex) for the treatment of macular edema associated with branch retinal vein occlusion. The patient had a history of herpes simplex virus keratitis that was quiescent for more than 30 years. Results: Clinical examination of the left eye showed arborizing epithelial ulcer with terminal bulbs consistent with herpes simplex virus keratitis. Conclusion: Quiescent herpes simplex virus keratitis can be reactivated after dexamethasone implant (Ozurdex). Prophylactic antiviral therapy might be indicated in individuals who have a high risk of recurrent herpetic disease.

Original languageEnglish (US)
Pages (from-to)296-297
Number of pages2
JournalRetinal Cases and Brief Reports
Volume11
Issue number4
DOIs
StatePublished - Jan 1 2017
Externally publishedYes

Keywords

  • Ozurdex
  • dexamethasone implant
  • herpes simplex keratitis
  • reactivation
  • recurrence

ASJC Scopus subject areas

  • Ophthalmology

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