Radial scanning and linear array endosonography for staging pancreatic cancer: A prospective randomized comparison

F. Gress, T. Savides, Oscar Cummings, Stuart Sherman, Glen Lehman, S. Zaidi, R. Hawes

Research output: Contribution to journalArticle

74 Citations (Scopus)

Abstract

Background: Endoscopic ultrasound (EUS) is known to be accurate for staging pancreatic cancer. Little data exist to determine if linear array or radial scanning EUS is superior for staging pancreatic cancer. This prospective comparison was undertaken to assess the accuracy of linear array and radial scanning EUS for staging pancreatic cancer. Methods: Patients with pancreatic cancer referred for EUS staging were randomized to linear array or radial scanning EUS. Staging accuracy for each was determined by comparison to surgical pathology in those patients going to surgery. Results: Seventy- nine patients with pancreatic cancer were enrolled and 33 had surgical resection. Of these, 17 patients were randomized to linear array and 16 to radial scanning EUS. The remaining 46 patients did not have surgery because of comorbid illness or clinically unresectable disease. EUS staging accuracy for linear array was 94% (16 of 17) for T and 71% (12 of 17) for N staging, whereas radial scanning was 88% (14 of 16) for T and 75% (12 of 16) for N staging. For predicting vascular invasion, radial scanning was 100% accurate (16 of 16) while linear array was 94% (16 of 17) accurate. There was one false-negative assessment of invasion using linear array EUS. Conclusion: Overall, both EUS designs appear equivalent for staging pancreatic cancer and assessing vascular invasion. In view of our findings and the capability for ultrasound-directed fine-needle aspiration with linear array EUS, this instrument may be the preferred choice for evaluating pancreatic masses.

Original languageEnglish
Pages (from-to)138-142
Number of pages5
JournalGastrointestinal Endoscopy
Volume45
Issue number2
DOIs
StatePublished - 1997

Fingerprint

Endosonography
Pancreatic Neoplasms
Blood Vessels
Surgical Pathology
Fine Needle Biopsy

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Radial scanning and linear array endosonography for staging pancreatic cancer : A prospective randomized comparison. / Gress, F.; Savides, T.; Cummings, Oscar; Sherman, Stuart; Lehman, Glen; Zaidi, S.; Hawes, R.

In: Gastrointestinal Endoscopy, Vol. 45, No. 2, 1997, p. 138-142.

Research output: Contribution to journalArticle

@article{f0dca74a55224433b6560791aa73510c,
title = "Radial scanning and linear array endosonography for staging pancreatic cancer: A prospective randomized comparison",
abstract = "Background: Endoscopic ultrasound (EUS) is known to be accurate for staging pancreatic cancer. Little data exist to determine if linear array or radial scanning EUS is superior for staging pancreatic cancer. This prospective comparison was undertaken to assess the accuracy of linear array and radial scanning EUS for staging pancreatic cancer. Methods: Patients with pancreatic cancer referred for EUS staging were randomized to linear array or radial scanning EUS. Staging accuracy for each was determined by comparison to surgical pathology in those patients going to surgery. Results: Seventy- nine patients with pancreatic cancer were enrolled and 33 had surgical resection. Of these, 17 patients were randomized to linear array and 16 to radial scanning EUS. The remaining 46 patients did not have surgery because of comorbid illness or clinically unresectable disease. EUS staging accuracy for linear array was 94{\%} (16 of 17) for T and 71{\%} (12 of 17) for N staging, whereas radial scanning was 88{\%} (14 of 16) for T and 75{\%} (12 of 16) for N staging. For predicting vascular invasion, radial scanning was 100{\%} accurate (16 of 16) while linear array was 94{\%} (16 of 17) accurate. There was one false-negative assessment of invasion using linear array EUS. Conclusion: Overall, both EUS designs appear equivalent for staging pancreatic cancer and assessing vascular invasion. In view of our findings and the capability for ultrasound-directed fine-needle aspiration with linear array EUS, this instrument may be the preferred choice for evaluating pancreatic masses.",
author = "F. Gress and T. Savides and Oscar Cummings and Stuart Sherman and Glen Lehman and S. Zaidi and R. Hawes",
year = "1997",
doi = "10.1016/S0016-5107(97)70236-0",
language = "English",
volume = "45",
pages = "138--142",
journal = "Gastrointestinal Endoscopy",
issn = "0016-5107",
publisher = "Mosby Inc.",
number = "2",

}

TY - JOUR

T1 - Radial scanning and linear array endosonography for staging pancreatic cancer

T2 - A prospective randomized comparison

AU - Gress, F.

AU - Savides, T.

AU - Cummings, Oscar

AU - Sherman, Stuart

AU - Lehman, Glen

AU - Zaidi, S.

AU - Hawes, R.

PY - 1997

Y1 - 1997

N2 - Background: Endoscopic ultrasound (EUS) is known to be accurate for staging pancreatic cancer. Little data exist to determine if linear array or radial scanning EUS is superior for staging pancreatic cancer. This prospective comparison was undertaken to assess the accuracy of linear array and radial scanning EUS for staging pancreatic cancer. Methods: Patients with pancreatic cancer referred for EUS staging were randomized to linear array or radial scanning EUS. Staging accuracy for each was determined by comparison to surgical pathology in those patients going to surgery. Results: Seventy- nine patients with pancreatic cancer were enrolled and 33 had surgical resection. Of these, 17 patients were randomized to linear array and 16 to radial scanning EUS. The remaining 46 patients did not have surgery because of comorbid illness or clinically unresectable disease. EUS staging accuracy for linear array was 94% (16 of 17) for T and 71% (12 of 17) for N staging, whereas radial scanning was 88% (14 of 16) for T and 75% (12 of 16) for N staging. For predicting vascular invasion, radial scanning was 100% accurate (16 of 16) while linear array was 94% (16 of 17) accurate. There was one false-negative assessment of invasion using linear array EUS. Conclusion: Overall, both EUS designs appear equivalent for staging pancreatic cancer and assessing vascular invasion. In view of our findings and the capability for ultrasound-directed fine-needle aspiration with linear array EUS, this instrument may be the preferred choice for evaluating pancreatic masses.

AB - Background: Endoscopic ultrasound (EUS) is known to be accurate for staging pancreatic cancer. Little data exist to determine if linear array or radial scanning EUS is superior for staging pancreatic cancer. This prospective comparison was undertaken to assess the accuracy of linear array and radial scanning EUS for staging pancreatic cancer. Methods: Patients with pancreatic cancer referred for EUS staging were randomized to linear array or radial scanning EUS. Staging accuracy for each was determined by comparison to surgical pathology in those patients going to surgery. Results: Seventy- nine patients with pancreatic cancer were enrolled and 33 had surgical resection. Of these, 17 patients were randomized to linear array and 16 to radial scanning EUS. The remaining 46 patients did not have surgery because of comorbid illness or clinically unresectable disease. EUS staging accuracy for linear array was 94% (16 of 17) for T and 71% (12 of 17) for N staging, whereas radial scanning was 88% (14 of 16) for T and 75% (12 of 16) for N staging. For predicting vascular invasion, radial scanning was 100% accurate (16 of 16) while linear array was 94% (16 of 17) accurate. There was one false-negative assessment of invasion using linear array EUS. Conclusion: Overall, both EUS designs appear equivalent for staging pancreatic cancer and assessing vascular invasion. In view of our findings and the capability for ultrasound-directed fine-needle aspiration with linear array EUS, this instrument may be the preferred choice for evaluating pancreatic masses.

UR - http://www.scopus.com/inward/record.url?scp=0031036409&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031036409&partnerID=8YFLogxK

U2 - 10.1016/S0016-5107(97)70236-0

DO - 10.1016/S0016-5107(97)70236-0

M3 - Article

C2 - 9040998

AN - SCOPUS:0031036409

VL - 45

SP - 138

EP - 142

JO - Gastrointestinal Endoscopy

JF - Gastrointestinal Endoscopy

SN - 0016-5107

IS - 2

ER -