Radiation-induced intracranial malignant gliomas

Scott Shapiro, J. Mealey, C. Sartorius

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

The authors present seven cases of malignant gliomas that occurred after radiation therapy administered for diseases different from the subsequent glial tumor. Included among these seven are three patients who were treated with interstitial brachytherapy. Previously reported cases of radiation-induced glioma are reviewed and analyzed for common characteristics. Children receiving central nervous system irradiation appear particularly susceptible to induction of malignant gliomas by radiation. Interstitial brachytherapy may be used successfully instead of external beam radiotherapy in previously irradiated, tumor-free brain, and thus may reduce the risk of radiation necrosis.

Original languageEnglish
Pages (from-to)77-82
Number of pages6
JournalJournal of Neurosurgery
Volume71
Issue number1
StatePublished - 1989

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Glioma
Brachytherapy
Radiation
Radiotherapy
Brain Neoplasms
Neuroglia
Necrosis
Central Nervous System
Neoplasms

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Shapiro, S., Mealey, J., & Sartorius, C. (1989). Radiation-induced intracranial malignant gliomas. Journal of Neurosurgery, 71(1), 77-82.

Radiation-induced intracranial malignant gliomas. / Shapiro, Scott; Mealey, J.; Sartorius, C.

In: Journal of Neurosurgery, Vol. 71, No. 1, 1989, p. 77-82.

Research output: Contribution to journalArticle

Shapiro, S, Mealey, J & Sartorius, C 1989, 'Radiation-induced intracranial malignant gliomas', Journal of Neurosurgery, vol. 71, no. 1, pp. 77-82.
Shapiro, Scott ; Mealey, J. ; Sartorius, C. / Radiation-induced intracranial malignant gliomas. In: Journal of Neurosurgery. 1989 ; Vol. 71, No. 1. pp. 77-82.
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