Radiation therapy in the treatment of partially resected meningiomas

Nicholas Barbaro, P. H. Gutin, C. B. Wilson, G. E. Sheline, E. B. Boldrey, W. M. Wara

Research output: Contribution to journalArticle

234 Citations (Scopus)

Abstract

To address the question of whether radiation therapy is beneficial in the management of partially resected meningiomas, we reviewed the records of all patients admitted to the University of California, San Francisco, between 1968 and 1978 who had a diagnosis of intracranial meningioma. The patients were divided into three groups: 51 patients had gross total resection and did not receive radiation therapy, 30 patients had subtotal resection and no radiation therapy, and 54 patients had subtotal resection followed by radiation therapy. The subtotal resection groups were similar in average age, male:female ratio, and tumor location, which allowed a valid comparison of the effects of irradiation. The recurrence rate in the total resection group was 4% (2 of 51 patients). Among patients in the subtotal resection groups, 60% of nonirradiated patients had a recurrence, compared with only 32% of the irradiated patients. The median time to recurrence was significantly longer in the irradiated group than in the nonirradiated group (125 vs. 66 months, P

Original languageEnglish (US)
Pages (from-to)525-528
Number of pages4
JournalNeurosurgery
Volume20
Issue number4
StatePublished - 1987
Externally publishedYes

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Meningioma
Radiotherapy
Therapeutics
Recurrence
San Francisco

ASJC Scopus subject areas

  • Clinical Neurology
  • Surgery

Cite this

Barbaro, N., Gutin, P. H., Wilson, C. B., Sheline, G. E., Boldrey, E. B., & Wara, W. M. (1987). Radiation therapy in the treatment of partially resected meningiomas. Neurosurgery, 20(4), 525-528.

Radiation therapy in the treatment of partially resected meningiomas. / Barbaro, Nicholas; Gutin, P. H.; Wilson, C. B.; Sheline, G. E.; Boldrey, E. B.; Wara, W. M.

In: Neurosurgery, Vol. 20, No. 4, 1987, p. 525-528.

Research output: Contribution to journalArticle

Barbaro, N, Gutin, PH, Wilson, CB, Sheline, GE, Boldrey, EB & Wara, WM 1987, 'Radiation therapy in the treatment of partially resected meningiomas', Neurosurgery, vol. 20, no. 4, pp. 525-528.
Barbaro N, Gutin PH, Wilson CB, Sheline GE, Boldrey EB, Wara WM. Radiation therapy in the treatment of partially resected meningiomas. Neurosurgery. 1987;20(4):525-528.
Barbaro, Nicholas ; Gutin, P. H. ; Wilson, C. B. ; Sheline, G. E. ; Boldrey, E. B. ; Wara, W. M. / Radiation therapy in the treatment of partially resected meningiomas. In: Neurosurgery. 1987 ; Vol. 20, No. 4. pp. 525-528.
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