Radical prostatectomy specimen processing: A critical appraisal of sampling methods

Ming Tse Sung, Darrell Davidson, Rodolfo Montironi, Antonio Lopez-Beltran, Liang Cheng

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Radical prostatectomy gives the most accurate and detailed information available for determining prognosis and deciding about adjuvant therapy for prostate cancer. The consistency and reproducibility of observations from these specimens requires a standardised protocol for tissue fixation, sampling, embedding and processing. Although the publication of processing protocols in recent years has led to a convergence of opinions, differences still exist in methods of handling, sampling and processing specimens. In this review article, we incorporate the processing methods for radical prostatectomy addressed in the previous reports and propose a comprehensively standardised approach to evaluate radical prostatectomy specimens.

Original languageEnglish
Pages (from-to)490-498
Number of pages9
JournalCurrent Diagnostic Pathology
Volume13
Issue number6
DOIs
StatePublished - Dec 2007

Fingerprint

Prostatectomy
Tissue Fixation
Publications
Prostatic Neoplasms
Therapeutics

Keywords

  • Pathological staging
  • Processing protocol
  • Prostatic neoplasm
  • Radical prostatectomy
  • Specimen-handling
  • Tissue procurement
  • Whole-mount method

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Radical prostatectomy specimen processing : A critical appraisal of sampling methods. / Sung, Ming Tse; Davidson, Darrell; Montironi, Rodolfo; Lopez-Beltran, Antonio; Cheng, Liang.

In: Current Diagnostic Pathology, Vol. 13, No. 6, 12.2007, p. 490-498.

Research output: Contribution to journalArticle

Sung, Ming Tse ; Davidson, Darrell ; Montironi, Rodolfo ; Lopez-Beltran, Antonio ; Cheng, Liang. / Radical prostatectomy specimen processing : A critical appraisal of sampling methods. In: Current Diagnostic Pathology. 2007 ; Vol. 13, No. 6. pp. 490-498.
@article{59ee4e17f00b49ecae196cbad71d666a,
title = "Radical prostatectomy specimen processing: A critical appraisal of sampling methods",
abstract = "Radical prostatectomy gives the most accurate and detailed information available for determining prognosis and deciding about adjuvant therapy for prostate cancer. The consistency and reproducibility of observations from these specimens requires a standardised protocol for tissue fixation, sampling, embedding and processing. Although the publication of processing protocols in recent years has led to a convergence of opinions, differences still exist in methods of handling, sampling and processing specimens. In this review article, we incorporate the processing methods for radical prostatectomy addressed in the previous reports and propose a comprehensively standardised approach to evaluate radical prostatectomy specimens.",
keywords = "Pathological staging, Processing protocol, Prostatic neoplasm, Radical prostatectomy, Specimen-handling, Tissue procurement, Whole-mount method",
author = "Sung, {Ming Tse} and Darrell Davidson and Rodolfo Montironi and Antonio Lopez-Beltran and Liang Cheng",
year = "2007",
month = "12",
doi = "10.1016/j.cdip.2007.06.005",
language = "English",
volume = "13",
pages = "490--498",
journal = "Diagnostic Histopathology",
issn = "1756-2317",
publisher = "Elsevier BV",
number = "6",

}

TY - JOUR

T1 - Radical prostatectomy specimen processing

T2 - A critical appraisal of sampling methods

AU - Sung, Ming Tse

AU - Davidson, Darrell

AU - Montironi, Rodolfo

AU - Lopez-Beltran, Antonio

AU - Cheng, Liang

PY - 2007/12

Y1 - 2007/12

N2 - Radical prostatectomy gives the most accurate and detailed information available for determining prognosis and deciding about adjuvant therapy for prostate cancer. The consistency and reproducibility of observations from these specimens requires a standardised protocol for tissue fixation, sampling, embedding and processing. Although the publication of processing protocols in recent years has led to a convergence of opinions, differences still exist in methods of handling, sampling and processing specimens. In this review article, we incorporate the processing methods for radical prostatectomy addressed in the previous reports and propose a comprehensively standardised approach to evaluate radical prostatectomy specimens.

AB - Radical prostatectomy gives the most accurate and detailed information available for determining prognosis and deciding about adjuvant therapy for prostate cancer. The consistency and reproducibility of observations from these specimens requires a standardised protocol for tissue fixation, sampling, embedding and processing. Although the publication of processing protocols in recent years has led to a convergence of opinions, differences still exist in methods of handling, sampling and processing specimens. In this review article, we incorporate the processing methods for radical prostatectomy addressed in the previous reports and propose a comprehensively standardised approach to evaluate radical prostatectomy specimens.

KW - Pathological staging

KW - Processing protocol

KW - Prostatic neoplasm

KW - Radical prostatectomy

KW - Specimen-handling

KW - Tissue procurement

KW - Whole-mount method

UR - http://www.scopus.com/inward/record.url?scp=35848955658&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=35848955658&partnerID=8YFLogxK

U2 - 10.1016/j.cdip.2007.06.005

DO - 10.1016/j.cdip.2007.06.005

M3 - Article

AN - SCOPUS:35848955658

VL - 13

SP - 490

EP - 498

JO - Diagnostic Histopathology

JF - Diagnostic Histopathology

SN - 1756-2317

IS - 6

ER -