Radioisotopic Detection of Osseous Metastases

Evaluation of 99mTc Polyphosphate and 99mTc Pyrophosphate

James Fletcher, Erica Solaric George, Robert E. Henry, Robert M. Donati

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

A total of 146 patients were investigated for the presence of osseous metastases with 99mTc polyphosphate or 99mTc pyrophosphate bone scans. Results of bone imaging were retrospectively compared to roentgenographic results surveying similar anatomic areas in 128 patients. This comparison revealed that roentgenographic interpretations were in error in 19% of the cases. Thirtythree patients had bone scans and roentgenograms that were in agreement and considered abnormal, but in more than one third of these cases the patients had multiple abnormalities that were shown by the bone scan but were not recognized roentgenographically. In consideration of the low toxicity, ready availability, economy, shortened procedure time, and low radiation dose associated with the use of these new bone-seeking agents, it is concluded that they are superior to roentgenograms and previously utilized radionuclides for early detection of osseous metastases.

Original languageEnglish (US)
Pages (from-to)553-557
Number of pages5
JournalArchives of Internal Medicine
Volume135
Issue number4
DOIs
StatePublished - 1975
Externally publishedYes

Fingerprint

Technetium Tc 99m Pyrophosphate
Polyphosphates
Neoplasm Metastasis
Bone and Bones
Multiple Abnormalities
Radioisotopes
Radiation

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Radioisotopic Detection of Osseous Metastases : Evaluation of 99mTc Polyphosphate and 99mTc Pyrophosphate. / Fletcher, James; Solaric George, Erica; Henry, Robert E.; Donati, Robert M.

In: Archives of Internal Medicine, Vol. 135, No. 4, 1975, p. 553-557.

Research output: Contribution to journalArticle

Fletcher, James ; Solaric George, Erica ; Henry, Robert E. ; Donati, Robert M. / Radioisotopic Detection of Osseous Metastases : Evaluation of 99mTc Polyphosphate and 99mTc Pyrophosphate. In: Archives of Internal Medicine. 1975 ; Vol. 135, No. 4. pp. 553-557.
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