Radiological diagnosis of drop metastases from paediatric brain tumours using combination of 2D and 3D MRI sequences

S. F. Kralik, Darren O'Neill, A. P. Kamer, E. Rodriguez, C. Y. Ho

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Aim To evaluate spinal magnetic resonance imaging (MRI) examinations using a combination of two-dimensional (2D) and three-dimensional (3D) MRI sequences for diagnosis of drop metastases. Materials and methods Fifty-five paediatric patients with primary brain tumours were evaluated for drop metastases at initial presentation using spinal MRI including sagittal 2D T1-weighted (W) contrast-enhanced (+C), axial 3D T1W+C volumetric interpolated breath-hold (VIBE), and sagittal 3D T2W SPACE (Sampling Perfection with Application optimised Contrasts using different flip angle Evolutions). Results The MRI false-negative rate was 4%, and cerebrospinal fluid (CSF) false-negative rate was 16% (p=0.07). The 3D T1W+C VIBE increased the number of drop metastases detected in 42% of patients. Drop metastases were more conspicuous in 25% of patients on 3D T2W SPACE. Conclusion Spinal MRI examinations including 2D and 3D sequences demonstrate characteristics that may improve radiological diagnosis of drop metastases.

Original languageEnglish (US)
Pages (from-to)902.e13-902.e19
JournalClinical Radiology
Volume72
Issue number10
DOIs
StatePublished - Oct 1 2017

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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