Rare and unusual histological variants of prostatic carcinoma: Clinical significance

Roberta Mazzucchelli, Antonio Lopez-Beltran, Liang Cheng, Marina Scarpelli, Ziya Kirkali, Rodolfo Montironi

Research output: Contribution to journalReview article

49 Scopus citations

Abstract

We review the clinicopathological features of the following unusual histological variants of prostatic carcinoma: small cell carcinoma, ductal adenocarcinoma, sarcomatoid (carcinosarcoma), basal cell, squamous cell and adenosquamous, and urothelial carcinoma. These variants are rare and account for 5-10% of carcinomas that originate in the prostate. Some develop from acinar adenocarcinoma after hormonal or radiation therapy. They are usually aggressive tumours that often present with secondary deposits. The outcome is generally poor. Only basal cell carcinoma is seen as a low-grade carcinoma.

Original languageEnglish (US)
Pages (from-to)1369-1374
Number of pages6
JournalBJU International
Volume102
Issue number10
DOIs
StatePublished - Nov 2008

Keywords

  • Carcinosarcoma
  • Ductal adenocarcinoma
  • Small cell carcinoma
  • Unusual carcinomas

ASJC Scopus subject areas

  • Urology

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