Ready, set, go! how protein kinase C manages dynamic signaling

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

In this issue of Chemistry & Biology, Antal and colleagues describe how phosphorylation optimizes the signaling range of protein kinase C (PKC) isoforms. Priming of these enzymes regulates intramolecular conformational changes, which reduces access to their diacylglycerol (DAG) binding C1 domains.

Original languageEnglish
Pages (from-to)433-434
Number of pages2
JournalChemistry and Biology
Volume21
Issue number4
DOIs
StatePublished - Apr 24 2014

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Phosphorylation
Diglycerides
Protein Kinase C
Protein Isoforms
Enzymes

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Molecular Biology
  • Clinical Biochemistry
  • Molecular Medicine
  • Pharmacology
  • Medicine(all)

Cite this

Ready, set, go! how protein kinase C manages dynamic signaling. / Stahelin, Robert.

In: Chemistry and Biology, Vol. 21, No. 4, 24.04.2014, p. 433-434.

Research output: Contribution to journalArticle

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