Real-time 3D tumor tracking based on 2D projections of implanted markers

Songan Mao, Huanmei Wu, Minghui Lu, Chee Wai Cheng

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In cancer radiation therapy, the treatment effectiveness is degraded greatly by the tumor respiratory motion during treatment delivery, induced by patient free breathing and organ motions. Advance treatment delivery techniques with image guidance helps to address the tumor motion challenges. However, real-time tumor localization is still a big concern as the respiratory motion dynamically changes its motion velocities, directions, and amplitude during treatment delivery. In this project, an optimized internal marker 3D localization method was proposed by combining the use of onboard kiovoltage (kV) beam and megavoltage (MV) imaging systems. Two sets of 2D projection images from any pair of kV-kV, kV-MV or MV-MV with different gantry rotation angles will be utilized to derive the 3D tumor positions. This approach transforms the projection 2D images to the original 3D location without requirements of the two imaging systems to be orthogonal. The accuracy of the proposed method was validated by several evaluation metrics. The average 3D Euclidean difference is between 0.21 mm to 0.56 mm, which is within the range of clinical applications. Further study will be carried out to evaluate the system comprehensively and integrate to the existing treatment delivery system for better communications among different systems. It potentially will improve the treatment accuracy and provide better health care to cancer patients. Copyright ISCA.

Original languageEnglish (US)
Title of host publicationProceedings of the 31st International Conference on Computers and Their Applications, CATA 2016
PublisherThe International Society for Computers and Their Applications (ISCA)
Pages177-182
Number of pages6
ISBN (Electronic)9781943436026
StatePublished - 2016
Event31st International Conference on Computers and Their Applications, CATA 2016 - Las Vegas, United States
Duration: Apr 4 2016Apr 6 2016

Other

Other31st International Conference on Computers and Their Applications, CATA 2016
CountryUnited States
CityLas Vegas
Period4/4/164/6/16

Fingerprint

Tumors
Imaging systems
Radiotherapy
Health care
Communication

Keywords

  • 3D marker localization
  • Dual imaging
  • Image guided radiation treatment

ASJC Scopus subject areas

  • Computer Science Applications

Cite this

Mao, S., Wu, H., Lu, M., & Cheng, C. W. (2016). Real-time 3D tumor tracking based on 2D projections of implanted markers. In Proceedings of the 31st International Conference on Computers and Their Applications, CATA 2016 (pp. 177-182). The International Society for Computers and Their Applications (ISCA).

Real-time 3D tumor tracking based on 2D projections of implanted markers. / Mao, Songan; Wu, Huanmei; Lu, Minghui; Cheng, Chee Wai.

Proceedings of the 31st International Conference on Computers and Their Applications, CATA 2016. The International Society for Computers and Their Applications (ISCA), 2016. p. 177-182.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Mao, S, Wu, H, Lu, M & Cheng, CW 2016, Real-time 3D tumor tracking based on 2D projections of implanted markers. in Proceedings of the 31st International Conference on Computers and Their Applications, CATA 2016. The International Society for Computers and Their Applications (ISCA), pp. 177-182, 31st International Conference on Computers and Their Applications, CATA 2016, Las Vegas, United States, 4/4/16.
Mao S, Wu H, Lu M, Cheng CW. Real-time 3D tumor tracking based on 2D projections of implanted markers. In Proceedings of the 31st International Conference on Computers and Their Applications, CATA 2016. The International Society for Computers and Their Applications (ISCA). 2016. p. 177-182
Mao, Songan ; Wu, Huanmei ; Lu, Minghui ; Cheng, Chee Wai. / Real-time 3D tumor tracking based on 2D projections of implanted markers. Proceedings of the 31st International Conference on Computers and Their Applications, CATA 2016. The International Society for Computers and Their Applications (ISCA), 2016. pp. 177-182
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