Recent trends in placenta accreta in the United States and its impact on maternal-fetal morbidity and healthcare-Associated costs, 1998-2011

Mulubrhan F. Mogos, Jason L. Salemi, Mary Ashley, Valerie E. Whiteman, Hamisu M. Salihu

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Objective: To describe the prevalence, trends, adverse maternal-fetal morbidities and healthcare costs associated with placenta accreta (PA) in the United States (US) between 1998 and 2011.Methods: A retrospective, cross-sectional analysis of inpatient hospital discharges was conducted using the National Inpatient Sample (NIS). We used International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) codes to identify both cases of PA and of selected comorbidities. Survey logistic regression was used to assess the association between PA and various maternal-fetal outcomes. Joinpoint regression modeling was used to estimate annual percent changes (APCs) in PA prevalence during the study period.Results: The prevalence of PA from 1998 to 2011 was 3.7 per 1000 delivery-related discharges. After adjusting for known or suspected confounders, PA conferred between a 20% to over a 19-fold increased odds of experiencing an adverse outcome. This resulted in a higher mean, per-hospitalization, cost of inpatient care after adjustment for inflation (5561 versus 4989), translating into over 115 million dollars in additional inpatient expenditures relative to non-PA affected deliveries from 2001 to 2011.Conclusions: This study updates recent trends in the prevalence of PA, which is valuable to clinicians and policymakers as they formulate targeted strategies to address factors related to PA.

Original languageEnglish (US)
Pages (from-to)1077-1082
Number of pages6
JournalJournal of Maternal-Fetal and Neonatal Medicine
Volume29
Issue number7
DOIs
StatePublished - Apr 2 2016

Fingerprint

Placenta Accreta
Health Care Costs
Mothers
Morbidity
Inpatients
International Classification of Diseases
Cross-Sectional Studies
Economic Inflation
Health Expenditures
Comorbidity
Hospitalization
Logistic Models
Costs and Cost Analysis

Keywords

  • Birth outcomes
  • cost
  • placenta accreta
  • pregnancy
  • trend

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

Cite this

Recent trends in placenta accreta in the United States and its impact on maternal-fetal morbidity and healthcare-Associated costs, 1998-2011. / Mogos, Mulubrhan F.; Salemi, Jason L.; Ashley, Mary; Whiteman, Valerie E.; Salihu, Hamisu M.

In: Journal of Maternal-Fetal and Neonatal Medicine, Vol. 29, No. 7, 02.04.2016, p. 1077-1082.

Research output: Contribution to journalArticle

Mogos, Mulubrhan F. ; Salemi, Jason L. ; Ashley, Mary ; Whiteman, Valerie E. ; Salihu, Hamisu M. / Recent trends in placenta accreta in the United States and its impact on maternal-fetal morbidity and healthcare-Associated costs, 1998-2011. In: Journal of Maternal-Fetal and Neonatal Medicine. 2016 ; Vol. 29, No. 7. pp. 1077-1082.
@article{0d23687476d740039e5e9591a734fc15,
title = "Recent trends in placenta accreta in the United States and its impact on maternal-fetal morbidity and healthcare-Associated costs, 1998-2011",
abstract = "Objective: To describe the prevalence, trends, adverse maternal-fetal morbidities and healthcare costs associated with placenta accreta (PA) in the United States (US) between 1998 and 2011.Methods: A retrospective, cross-sectional analysis of inpatient hospital discharges was conducted using the National Inpatient Sample (NIS). We used International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) codes to identify both cases of PA and of selected comorbidities. Survey logistic regression was used to assess the association between PA and various maternal-fetal outcomes. Joinpoint regression modeling was used to estimate annual percent changes (APCs) in PA prevalence during the study period.Results: The prevalence of PA from 1998 to 2011 was 3.7 per 1000 delivery-related discharges. After adjusting for known or suspected confounders, PA conferred between a 20{\%} to over a 19-fold increased odds of experiencing an adverse outcome. This resulted in a higher mean, per-hospitalization, cost of inpatient care after adjustment for inflation (5561 versus 4989), translating into over 115 million dollars in additional inpatient expenditures relative to non-PA affected deliveries from 2001 to 2011.Conclusions: This study updates recent trends in the prevalence of PA, which is valuable to clinicians and policymakers as they formulate targeted strategies to address factors related to PA.",
keywords = "Birth outcomes, cost, placenta accreta, pregnancy, trend",
author = "Mogos, {Mulubrhan F.} and Salemi, {Jason L.} and Mary Ashley and Whiteman, {Valerie E.} and Salihu, {Hamisu M.}",
year = "2016",
month = "4",
day = "2",
doi = "10.3109/14767058.2015.1034103",
language = "English (US)",
volume = "29",
pages = "1077--1082",
journal = "Journal of Maternal-Fetal and Neonatal Medicine",
issn = "1476-7058",
publisher = "Informa Healthcare",
number = "7",

}

TY - JOUR

T1 - Recent trends in placenta accreta in the United States and its impact on maternal-fetal morbidity and healthcare-Associated costs, 1998-2011

AU - Mogos, Mulubrhan F.

AU - Salemi, Jason L.

AU - Ashley, Mary

AU - Whiteman, Valerie E.

AU - Salihu, Hamisu M.

PY - 2016/4/2

Y1 - 2016/4/2

N2 - Objective: To describe the prevalence, trends, adverse maternal-fetal morbidities and healthcare costs associated with placenta accreta (PA) in the United States (US) between 1998 and 2011.Methods: A retrospective, cross-sectional analysis of inpatient hospital discharges was conducted using the National Inpatient Sample (NIS). We used International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) codes to identify both cases of PA and of selected comorbidities. Survey logistic regression was used to assess the association between PA and various maternal-fetal outcomes. Joinpoint regression modeling was used to estimate annual percent changes (APCs) in PA prevalence during the study period.Results: The prevalence of PA from 1998 to 2011 was 3.7 per 1000 delivery-related discharges. After adjusting for known or suspected confounders, PA conferred between a 20% to over a 19-fold increased odds of experiencing an adverse outcome. This resulted in a higher mean, per-hospitalization, cost of inpatient care after adjustment for inflation (5561 versus 4989), translating into over 115 million dollars in additional inpatient expenditures relative to non-PA affected deliveries from 2001 to 2011.Conclusions: This study updates recent trends in the prevalence of PA, which is valuable to clinicians and policymakers as they formulate targeted strategies to address factors related to PA.

AB - Objective: To describe the prevalence, trends, adverse maternal-fetal morbidities and healthcare costs associated with placenta accreta (PA) in the United States (US) between 1998 and 2011.Methods: A retrospective, cross-sectional analysis of inpatient hospital discharges was conducted using the National Inpatient Sample (NIS). We used International Classification of Diseases, Ninth Edition, Clinical Modification (ICD-9-CM) codes to identify both cases of PA and of selected comorbidities. Survey logistic regression was used to assess the association between PA and various maternal-fetal outcomes. Joinpoint regression modeling was used to estimate annual percent changes (APCs) in PA prevalence during the study period.Results: The prevalence of PA from 1998 to 2011 was 3.7 per 1000 delivery-related discharges. After adjusting for known or suspected confounders, PA conferred between a 20% to over a 19-fold increased odds of experiencing an adverse outcome. This resulted in a higher mean, per-hospitalization, cost of inpatient care after adjustment for inflation (5561 versus 4989), translating into over 115 million dollars in additional inpatient expenditures relative to non-PA affected deliveries from 2001 to 2011.Conclusions: This study updates recent trends in the prevalence of PA, which is valuable to clinicians and policymakers as they formulate targeted strategies to address factors related to PA.

KW - Birth outcomes

KW - cost

KW - placenta accreta

KW - pregnancy

KW - trend

UR - http://www.scopus.com/inward/record.url?scp=84955306928&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84955306928&partnerID=8YFLogxK

U2 - 10.3109/14767058.2015.1034103

DO - 10.3109/14767058.2015.1034103

M3 - Article

VL - 29

SP - 1077

EP - 1082

JO - Journal of Maternal-Fetal and Neonatal Medicine

JF - Journal of Maternal-Fetal and Neonatal Medicine

SN - 1476-7058

IS - 7

ER -