Recovery of Chlamydia trachomatis from endometrial and fallopian tube biopsies in women with infertility of tubal origin

M. K. Shepard, R. B. Jones

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

In order to examine the role of chronic active chlamydial infection in tubal infertility, cultures of Chlamydia trachomatis were performed on endometrial biopsies from 38, and fallopian tube biopsies from all, of 52 women undergoing tubal surgery for infertility. C. trachomatis was recovered from one or both sites in 8 of 52 (15%). Five of 6 women with positive fallopian tube cultures had endometrial cultures performed, and of these, 4 (80%) were positive. Three culture-positive women had been treated with tetracycline or doxycycline. Multiple blind passage in tissue culture was required for recovery of all six fallopian tube and four of the six endometrial isolates. No specific anatomic lesion was associated with documented infection. Chronic active chlamydial infection is frequently associated with tubal infertility, may persist despite therapy, and often can be detected by endometrial biopsy culture.

Original languageEnglish (US)
Pages (from-to)232-238
Number of pages7
JournalFertility and Sterility
Volume52
Issue number2
StatePublished - Jan 1 1989

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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