Recurrent genitourinary chlamydial infections in sexually active female adolescents

Margaret J. Blythe, Barry Katz, Byron Batteiger, Judith A. Ganser, Robert B. Jones

Research output: Contribution to journalArticle

95 Citations (Scopus)

Abstract

To determine the recurrence rate of chlamydial infections, we initially screened an urban population of 1308 sexually active female adolescents for chlamydial infection at the urethral and endocervical sites; these young women were followed and had additional examinations for infection. Chlamydial infection was documented by tissue culture in 31.1% (407) of them at some time during the study. After appropriate antibiotic treatment, 68.3% (278/407) returned for test-of-cure cultures within 3 months of their initial infection; of those 278, a total of 254 had sterile cultures. These patients were followed to determine the recurrence rate of chlamydial infections. Of these 254 patients, 177 (69.7%) had one or more follow-up visits; 38.4% (68/177) had a recurrent chlamydial infection. The majority of recurrent infections were documented within 9 months of the initial infection. Recurrent infections with the same serovar were frequent, suggesting reinfection by untreated partners or possible relapse of the initial chlamydial infection. This high rate of recurrent infection suggests that female adolescents should be rescreened frequently for genitourinary chlamydial infections.

Original languageEnglish
Pages (from-to)487-493
Number of pages7
JournalJournal of Pediatrics
Volume121
Issue number3
DOIs
StatePublished - 1992

Fingerprint

Infection
Recurrence
Urban Population
Anti-Bacterial Agents

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Recurrent genitourinary chlamydial infections in sexually active female adolescents. / Blythe, Margaret J.; Katz, Barry; Batteiger, Byron; Ganser, Judith A.; Jones, Robert B.

In: Journal of Pediatrics, Vol. 121, No. 3, 1992, p. 487-493.

Research output: Contribution to journalArticle

Blythe, Margaret J. ; Katz, Barry ; Batteiger, Byron ; Ganser, Judith A. ; Jones, Robert B. / Recurrent genitourinary chlamydial infections in sexually active female adolescents. In: Journal of Pediatrics. 1992 ; Vol. 121, No. 3. pp. 487-493.
@article{a1a0b8b6da2841b88197c9fc196f9fda,
title = "Recurrent genitourinary chlamydial infections in sexually active female adolescents",
abstract = "To determine the recurrence rate of chlamydial infections, we initially screened an urban population of 1308 sexually active female adolescents for chlamydial infection at the urethral and endocervical sites; these young women were followed and had additional examinations for infection. Chlamydial infection was documented by tissue culture in 31.1{\%} (407) of them at some time during the study. After appropriate antibiotic treatment, 68.3{\%} (278/407) returned for test-of-cure cultures within 3 months of their initial infection; of those 278, a total of 254 had sterile cultures. These patients were followed to determine the recurrence rate of chlamydial infections. Of these 254 patients, 177 (69.7{\%}) had one or more follow-up visits; 38.4{\%} (68/177) had a recurrent chlamydial infection. The majority of recurrent infections were documented within 9 months of the initial infection. Recurrent infections with the same serovar were frequent, suggesting reinfection by untreated partners or possible relapse of the initial chlamydial infection. This high rate of recurrent infection suggests that female adolescents should be rescreened frequently for genitourinary chlamydial infections.",
author = "Blythe, {Margaret J.} and Barry Katz and Byron Batteiger and Ganser, {Judith A.} and Jones, {Robert B.}",
year = "1992",
doi = "10.1016/S0022-3476(05)81812-8",
language = "English",
volume = "121",
pages = "487--493",
journal = "Journal of Pediatrics",
issn = "0022-3476",
publisher = "Mosby Inc.",
number = "3",

}

TY - JOUR

T1 - Recurrent genitourinary chlamydial infections in sexually active female adolescents

AU - Blythe, Margaret J.

AU - Katz, Barry

AU - Batteiger, Byron

AU - Ganser, Judith A.

AU - Jones, Robert B.

PY - 1992

Y1 - 1992

N2 - To determine the recurrence rate of chlamydial infections, we initially screened an urban population of 1308 sexually active female adolescents for chlamydial infection at the urethral and endocervical sites; these young women were followed and had additional examinations for infection. Chlamydial infection was documented by tissue culture in 31.1% (407) of them at some time during the study. After appropriate antibiotic treatment, 68.3% (278/407) returned for test-of-cure cultures within 3 months of their initial infection; of those 278, a total of 254 had sterile cultures. These patients were followed to determine the recurrence rate of chlamydial infections. Of these 254 patients, 177 (69.7%) had one or more follow-up visits; 38.4% (68/177) had a recurrent chlamydial infection. The majority of recurrent infections were documented within 9 months of the initial infection. Recurrent infections with the same serovar were frequent, suggesting reinfection by untreated partners or possible relapse of the initial chlamydial infection. This high rate of recurrent infection suggests that female adolescents should be rescreened frequently for genitourinary chlamydial infections.

AB - To determine the recurrence rate of chlamydial infections, we initially screened an urban population of 1308 sexually active female adolescents for chlamydial infection at the urethral and endocervical sites; these young women were followed and had additional examinations for infection. Chlamydial infection was documented by tissue culture in 31.1% (407) of them at some time during the study. After appropriate antibiotic treatment, 68.3% (278/407) returned for test-of-cure cultures within 3 months of their initial infection; of those 278, a total of 254 had sterile cultures. These patients were followed to determine the recurrence rate of chlamydial infections. Of these 254 patients, 177 (69.7%) had one or more follow-up visits; 38.4% (68/177) had a recurrent chlamydial infection. The majority of recurrent infections were documented within 9 months of the initial infection. Recurrent infections with the same serovar were frequent, suggesting reinfection by untreated partners or possible relapse of the initial chlamydial infection. This high rate of recurrent infection suggests that female adolescents should be rescreened frequently for genitourinary chlamydial infections.

UR - http://www.scopus.com/inward/record.url?scp=0026671728&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026671728&partnerID=8YFLogxK

U2 - 10.1016/S0022-3476(05)81812-8

DO - 10.1016/S0022-3476(05)81812-8

M3 - Article

VL - 121

SP - 487

EP - 493

JO - Journal of Pediatrics

JF - Journal of Pediatrics

SN - 0022-3476

IS - 3

ER -