Red-emitting pyrene-benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect

Chathura S. Abeywickrama, Kaveesha J. Wijesinghe, Robert V. Stahelin, Yi Pang

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

A series of pyrene-benzothiazolium probes were synthesized. By replacing the pyridinium with a benzothiazolium unit, the selectivity of pyrene-derivatives is found to switch from nuclear to cellular lysosomes. New probes do not require proton participation and exhibit high biocompatibility and long-term imaging ability.

Original languageEnglish (US)
Pages (from-to)3469-3472
Number of pages4
JournalChemical Communications
Volume55
Issue number24
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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