Red-emitting pyrene-benzothiazolium: unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect

Chathura S. Abeywickrama, Kaveesha J. Wijesinghe, Robert Stahelin, Yi Pang

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

A series of pyrene-benzothiazolium probes were synthesized. By replacing the pyridinium with a benzothiazolium unit, the selectivity of pyrene-derivatives is found to switch from nuclear to cellular lysosomes. New probes do not require proton participation and exhibit high biocompatibility and long-term imaging ability.

Original languageEnglish (US)
Pages (from-to)3469-3472
Number of pages4
JournalChemical Communications
Volume55
Issue number24
DOIs
StatePublished - Jan 1 2019
Externally publishedYes

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Pyrene
Imaging techniques
Biocompatibility
Protons
Switches
Derivatives
pyrene

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Red-emitting pyrene-benzothiazolium : unexpected selectivity to lysosomes for real-time cell imaging without alkalinizing effect. / Abeywickrama, Chathura S.; Wijesinghe, Kaveesha J.; Stahelin, Robert; Pang, Yi.

In: Chemical Communications, Vol. 55, No. 24, 01.01.2019, p. 3469-3472.

Research output: Contribution to journalArticle

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