Redefining the Target Again: Chemotherapeutics as Vascular Disrupting Agents?

Research output: Contribution to journalArticle

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Abstract

In this issue of Cancer Cell, Shaked et al. (2008) provide novel mechanistic evidence that some chemotherapeutics induce circulating endothelial progenitor (CEP) mobilization with subsequent homing to tumor vasculature. Addition of an anti-VEGFR2 antibody increased antitumor activity only in combination with CEP-mobilizing chemotherapeutics. Here we discuss the implications of this work.

Original languageEnglish
Pages (from-to)195-196
Number of pages2
JournalCancer Cell
Volume14
Issue number3
DOIs
StatePublished - Sep 9 2008

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Blood Vessels
Anti-Idiotypic Antibodies
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Cell Biology
  • Oncology

Cite this

Redefining the Target Again : Chemotherapeutics as Vascular Disrupting Agents? / Polar, Yesim; Miller, Kathy.

In: Cancer Cell, Vol. 14, No. 3, 09.09.2008, p. 195-196.

Research output: Contribution to journalArticle

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