Regulation of expression of the fibronectin-binding protein BBK32 in Borrelia burgdorferi

Ming He, Bethany K. Boardman, Dalai Yan, X. Yang

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

The BBK32 protein binds to host extracellular ligand fibronectin and contributes to the pathogenesis of Borrelia burgdorferi. Here we showed that expression of the BBK32 gene is influenced by multiple environmental factors and that its regulation is governed by the response regulator Rrp2 and RpoN-RpoS (σ54S) sigma cascade in B. burgdorferi.

Original languageEnglish
Pages (from-to)8377-8380
Number of pages4
JournalJournal of Bacteriology
Volume189
Issue number22
DOIs
StatePublished - Nov 2007

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Borrelia burgdorferi
Fibronectins
Carrier Proteins
Ligands
Gene Expression
Proteins

ASJC Scopus subject areas

  • Applied Microbiology and Biotechnology
  • Immunology

Cite this

Regulation of expression of the fibronectin-binding protein BBK32 in Borrelia burgdorferi. / He, Ming; Boardman, Bethany K.; Yan, Dalai; Yang, X.

In: Journal of Bacteriology, Vol. 189, No. 22, 11.2007, p. 8377-8380.

Research output: Contribution to journalArticle

He, Ming ; Boardman, Bethany K. ; Yan, Dalai ; Yang, X. / Regulation of expression of the fibronectin-binding protein BBK32 in Borrelia burgdorferi. In: Journal of Bacteriology. 2007 ; Vol. 189, No. 22. pp. 8377-8380.
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