Relationship between left atrial size and echocardiographic left ventricular diastolic filling indices in patient with hypertension

A. Sherzov, M. Hurley, D. Sadler, John Brown, D. Hodges, E. Vanderbush, C. Francis

Research output: Contribution to journalArticle

Abstract

Determinants of LA dilation In patients (pis) with hypertension (HTN) have not been well evaluated. We studied the relationship between LV diastolic filling indices and left atrlal (LA) size In 122 HTN pts and 60 healthy controls. All pts were in sinus rhythm without evidence of structural heart disease. LA size, peak early mitral inflow velocity. (E), peak late mitral inflow velocity (A). E/A ratio (E/A), mitral inflow deceleration time (DT), Isovolumlc relaxation time (VRT) and LV mass index were obtained using standard methods. When diastolic filling Indices between pts with dilated and normal LA were compared, statistically significant difference was observed in: A (77.3 vs 61.3 cm/s p4 cm) LA (61 vs 12 p 0.0002). Age, sex. and heart rate were comparable In pts with HTN and controls. Among hypertensive pts 75% with dilated LA and 54% with normal LA had abnormal diastolic indices. There was no statistical difference in E/A, IVRT and DT between HTN pts with increased and normal LV mass index. By multivariate analysis peak A, DT, BSA, sex and LV mass index were shown to be independently associated with LA size (p

Original languageEnglish (US)
JournalJournal of Investigative Medicine
Volume44
Issue number3
StatePublished - 1996
Externally publishedYes

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Deceleration
Hypertension
Relaxation time
Dilatation
Heart Diseases
Multivariate Analysis
Heart Rate

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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Relationship between left atrial size and echocardiographic left ventricular diastolic filling indices in patient with hypertension. / Sherzov, A.; Hurley, M.; Sadler, D.; Brown, John; Hodges, D.; Vanderbush, E.; Francis, C.

In: Journal of Investigative Medicine, Vol. 44, No. 3, 1996.

Research output: Contribution to journalArticle

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AU - Sherzov, A.

AU - Hurley, M.

AU - Sadler, D.

AU - Brown, John

AU - Hodges, D.

AU - Vanderbush, E.

AU - Francis, C.

PY - 1996

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